ESXN_MYCTO
ID ESXN_MYCTO Reviewed; 94 AA.
AC P9WNJ2; L0TAM3; O53942; P0A570;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 33.
DE RecName: Full=ESAT-6-like protein EsxN {ECO:0000250|UniProtKB:P9WNJ3};
GN Name=esxN {ECO:0000250|UniProtKB:P9WNJ3}; OrderedLocusNames=MT1842;
GN ORFNames=MTV049.15;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P9WNJ3}.
CC Note=Secreted via the ESX-5 / type VII secretion system (T7SS).
CC {ECO:0000250|UniProtKB:P9WNJ3}.
CC -!- SIMILARITY: Belongs to the WXG100 family. ESAT-6 subfamily.
CC {ECO:0000305}.
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DR EMBL; AE000516; AAK46113.1; -; Genomic_DNA.
DR PIR; B70930; B70930.
DR RefSeq; WP_003408840.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WNJ2; -.
DR SMR; P9WNJ2; -.
DR EnsemblBacteria; AAK46113; AAK46113; MT1842.
DR GeneID; 45426331; -.
DR KEGG; mtc:MT1842; -.
DR PATRIC; fig|83331.31.peg.1984; -.
DR HOGENOM; CLU_192559_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR009416; ESAT-6-like_Myco.
DR InterPro; IPR036689; ESAT-6-like_sf.
DR InterPro; IPR010310; T7SS_ESAT-6-like.
DR Pfam; PF06013; WXG100; 1.
DR PIRSF; PIRSF037656; DUF1066; 1.
DR SUPFAM; SSF140453; SSF140453; 1.
PE 3: Inferred from homology;
KW Secreted.
FT CHAIN 1..94
FT /note="ESAT-6-like protein EsxN"
FT /id="PRO_0000427117"
SQ SEQUENCE 94 AA; 9942 MW; 1B7AE4913129C8D8 CRC64;
MTINYQFGDV DAHGAMIRAQ AASLEAEHQA IVRDVLAAGD FWGGAGSVAC QEFITQLGRN
FQVIYEQANA HGQKVQAAGN NMAQTDSAVG SSWA