ESXP_MYCTO
ID ESXP_MYCTO Reviewed; 98 AA.
AC P9WNI4; L0T9J5; P95243;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 31.
DE RecName: Full=ESAT-6-like protein EsxP {ECO:0000250|UniProtKB:P9WNI5};
GN Name=esxP {ECO:0000250|UniProtKB:P9WNI5}; OrderedLocusNames=MT2412;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- SUBUNIT: Forms a complex with EsxO. {ECO:0000250|UniProtKB:P9WNI5}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P9WNI5}.
CC Note=Probably secreted via the ESX-5 / type VII secretion system
CC (T7SS). {ECO:0000250|UniProtKB:P9WNI5}.
CC -!- SIMILARITY: Belongs to the WXG100 family. CFP-10 subfamily.
CC {ECO:0000305}.
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DR EMBL; AE000516; AAK46705.1; -; Genomic_DNA.
DR PIR; D70662; D70662.
DR RefSeq; WP_003900502.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WNI4; -.
DR SMR; P9WNI4; -.
DR EnsemblBacteria; AAK46705; AAK46705; MT2412.
DR KEGG; mtc:MT2412; -.
DR PATRIC; fig|83331.31.peg.1334; -.
DR HOGENOM; CLU_171031_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR036689; ESAT-6-like_sf.
DR InterPro; IPR010310; T7SS_ESAT-6-like.
DR Pfam; PF06013; WXG100; 1.
DR SUPFAM; SSF140453; SSF140453; 1.
DR TIGRFAMs; TIGR03930; WXG100_ESAT6; 1.
PE 3: Inferred from homology;
KW Secreted.
FT CHAIN 1..98
FT /note="ESAT-6-like protein EsxP"
FT /id="PRO_0000427121"
SQ SEQUENCE 98 AA; 10977 MW; 5AC41DEE70F269D6 CRC64;
MATRFMTDPH AMRDMAGRFE VHAQTVEDEA RRMWASAQNI SGAGWSGMAE ATSLDTMAQM
NQAFRNIVNM LHGVRDGLVR DANNYEQQEQ ASQQILSS