ID   ESXR_MYCLE              Reviewed;          96 AA.
AC   Q9CD33;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=ESAT-6-like protein EsxR {ECO:0000250|UniProtKB:P9WNI9};
GN   Name=esxR {ECO:0000250|UniProtKB:P9WNI9}; OrderedLocusNames=ML2531;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P9WNI9}.
CC       Note=Probably secreted via the ESX-3 / type VII secretion system
CC       (T7SS). {ECO:0000250|UniProtKB:P9WNI9}.
CC   -!- SIMILARITY: Belongs to the WXG100 family. ESAT-6 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AL583926; CAC32062.1; -; Genomic_DNA.
DR   PIR; H87225; H87225.
DR   RefSeq; NP_302626.1; NC_002677.1.
DR   RefSeq; WP_010908945.1; NC_002677.1.
DR   AlphaFoldDB; Q9CD33; -.
DR   SMR; Q9CD33; -.
DR   STRING; 272631.ML2531; -.
DR   EnsemblBacteria; CAC32062; CAC32062; CAC32062.
DR   KEGG; mle:ML2531; -.
DR   PATRIC; fig|272631.5.peg.4862; -.
DR   Leproma; ML2531; -.
DR   eggNOG; COG4842; Bacteria.
DR   HOGENOM; CLU_2451485_0_0_11; -.
DR   OMA; HEANTMS; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR036689; ESAT-6-like_sf.
DR   InterPro; IPR010310; T7SS_ESAT-6-like.
DR   Pfam; PF06013; WXG100; 1.
DR   SUPFAM; SSF140453; SSF140453; 1.
DR   TIGRFAMs; TIGR03930; WXG100_ESAT6; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Secreted.
FT   CHAIN           1..96
FT                   /note="ESAT-6-like protein EsxR"
FT                   /id="PRO_0000167812"
SQ   SEQUENCE   96 AA;  10393 MW;  E103DCC33D82B518 CRC64;
     MTQIMYNYPA MLDHAGNMSA CAGALQGVGI DIAAEQAALQ ACWGGDTGIS YQAWQVQWNQ
     ATEEMVRAYH AMANTHQNNT LAMLTRDQAE AAKWGG