ID   ESXR_MYCTO              Reviewed;          96 AA.
AC   P9WNI8; L0TBJ7; O53266; P64093;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 30.
DE   RecName: Full=ESAT-6-like protein EsxR {ECO:0000250|UniProtKB:P9WNI9};
GN   Name=esxR {ECO:0000250|UniProtKB:P9WNI9}; OrderedLocusNames=MT3104;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P9WNI9}.
CC       Note=Probably secreted via the ESX-3 / type VII secretion system
CC       (T7SS). {ECO:0000250|UniProtKB:P9WNI9}.
CC   -!- SIMILARITY: Belongs to the WXG100 family. ESAT-6 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE000516; AAK47433.1; -; Genomic_DNA.
DR   PIR; F70857; F70857.
DR   RefSeq; WP_003415340.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WNI8; -.
DR   SMR; P9WNI8; -.
DR   EnsemblBacteria; AAK47433; AAK47433; MT3104.
DR   KEGG; mtc:MT3104; -.
DR   PATRIC; fig|83331.31.peg.3345; -.
DR   HOGENOM; CLU_2451485_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR036689; ESAT-6-like_sf.
DR   InterPro; IPR010310; T7SS_ESAT-6-like.
DR   Pfam; PF06013; WXG100; 1.
DR   SUPFAM; SSF140453; SSF140453; 1.
DR   TIGRFAMs; TIGR03930; WXG100_ESAT6; 1.
PE   3: Inferred from homology;
KW   Secreted.
FT   CHAIN           1..96
FT                   /note="ESAT-6-like protein EsxR"
FT                   /id="PRO_0000427119"
SQ   SEQUENCE   96 AA;  10312 MW;  6BA858B058854D46 CRC64;
     MSQIMYNYPA MMAHAGDMAG YAGTLQSLGA DIASEQAVLS SAWQGDTGIT YQGWQTQWNQ
     ALEDLVRAYQ SMSGTHESNT MAMLARDGAE AAKWGG