ET1_ARATH
ID ET1_ARATH Reviewed; 506 AA.
AC F4JU69; O04047; Q9SZI8;
DT 13-APR-2016, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 61.
DE RecName: Full=Protein EFFECTOR OF TRANSCRIPTION 1 {ECO:0000303|PubMed:17991462};
DE Short=AtET1 {ECO:0000303|PubMed:17991462};
GN Name=ET1 {ECO:0000303|PubMed:17991462};
GN OrderedLocusNames=At4g26170 {ECO:0000312|Araport:AT4G26170};
GN ORFNames=F20B18.280 {ECO:0000312|EMBL:CAB39682.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 163-506.
RC TISSUE=Seed;
RA Wohlfarth T.;
RT "Arabidopsis thaliana mRNA for putative transcription factor.";
RL Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND GIY-YIG DOMAIN.
RX PubMed=17991462; DOI=10.1016/j.ydbio.2007.09.061;
RA Ivanov R., Tiedemann J., Czihal A., Schallau A., Diep L.H., Mock H.P.,
RA Claus B., Tewes A., Baeumlein H.;
RT "EFFECTOR OF TRANSCRIPTION2 is involved in xylem differentiation and
RT includes a functional DNA single strand cutting domain.";
RL Dev. Biol. 313:93-106(2008).
RN [5]
RP FUNCTION.
RX PubMed=22226340; DOI=10.1016/j.jplph.2011.11.017;
RA Ivanov R., Tiedemann J., Czihal A., Baumlein H.;
RT "Transcriptional regulator AtET2 is required for the induction of dormancy
RT during late seed development.";
RL J. Plant Physiol. 169:501-508(2012).
CC -!- FUNCTION: Transcriptional regulator involved in the regulation of cell
CC differentiation in meristems (By similarity). Binds DNA without
CC sequence preference (PubMed:22226340). {ECO:0000250|UniProtKB:F4K933,
CC ECO:0000269|PubMed:22226340}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:17991462}. Nucleus
CC {ECO:0000269|PubMed:17991462}. Note=Localizes to the cytoplasm in non-
CC differentiating cells and to the nucleus in differentiating cells.
CC {ECO:0000269|PubMed:17991462}.
CC -!- TISSUE SPECIFICITY: Expressed in rosette leaves, stipules, stems,
CC flowers, siliques and mature seeds. Expressed in the vascular bundles
CC of xylem in shoot parenchyma cells. Expressed in the remnant cytoplasm
CC of differentiated fiber cells and in protoxylem element of parenchymal
CC cells. {ECO:0000269|PubMed:17991462}.
CC -!- DOMAIN: Contains a bacterial GIY-YIG-like domain.
CC {ECO:0000305|PubMed:17991462}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB39682.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB79472.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL049483; CAB39682.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161564; CAB79472.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE85166.1; -; Genomic_DNA.
DR EMBL; Y10013; CAA71119.1; -; mRNA.
DR PIR; A85303; A85303.
DR PIR; T04272; T04272.
DR RefSeq; NP_194347.4; NM_118750.8.
DR AlphaFoldDB; F4JU69; -.
DR STRING; 3702.AT4G26170.1; -.
DR PaxDb; F4JU69; -.
DR PRIDE; F4JU69; -.
DR EnsemblPlants; AT4G26170.1; AT4G26170.1; AT4G26170.
DR GeneID; 828723; -.
DR Gramene; AT4G26170.1; AT4G26170.1; AT4G26170.
DR KEGG; ath:AT4G26170; -.
DR Araport; AT4G26170; -.
DR TAIR; locus:2120869; AT4G26170.
DR eggNOG; ENOG502QXNF; Eukaryota.
DR HOGENOM; CLU_539022_0_0_1; -.
DR InParanoid; F4JU69; -.
DR OMA; RRCWQHK; -.
DR OrthoDB; 431818at2759; -.
DR PRO; PR:F4JU69; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; F4JU69; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR GO; GO:0006306; P:DNA methylation; IGI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR InterPro; IPR038909; Effector_transcript.
DR PANTHER; PTHR35133; PTHR35133; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; DNA-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..506
FT /note="Protein EFFECTOR OF TRANSCRIPTION 1"
FT /id="PRO_0000436018"
FT DOMAIN 185..225
FT /note="GIY-YIG"
FT /evidence="ECO:0000305|PubMed:17991462"
FT REPEAT 306..331
FT /note="Cx9Cx9RCx2HK"
FT /evidence="ECO:0000305|PubMed:17991462"
FT REPEAT 361..386
FT /note="Cx9Cx9RCx2HK"
FT /evidence="ECO:0000305|PubMed:17991462"
FT REPEAT 428..453
FT /note="Cx9Cx9RCx2HK"
FT /evidence="ECO:0000305|PubMed:17991462"
FT REPEAT 475..500
FT /note="Cx9Cx9RCx2HK"
FT /evidence="ECO:0000305|PubMed:17991462"
FT REGION 234..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 404..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..268
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..284
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 506 AA; 57003 MW; 3992102C6E7C2E4E CRC64;
MLVVLQIHSS INVKVFASRL RKHFFFTRRK ITRIATCLSS SRCPLYPSHW NLCRWNNKQG
GTEIGLLIGG LIVFRQTLKS DQETKREQKK RDWILVTAFP SPSCSPCSRE TTTFELIMTP
FFQSGRVSPD LCFCVNPFQK LQNSQDFCGL LLNFSRFRSK AKGANEKENF REGKDLVGRN
RVQGAFQGLY ELSHDHGRKD DVLVANLGQP ESIRSRLRSY SRSFAHHDLL KQGLSQTILP
TTQNKSDNQT EEKKSDSEEE REVSSDAAEK ESNSLPSILR LSRSRPQPVS EKHDDIVDES
DSASACGVLL EDGTTCTTTP VKGRKRCTEH KGKRLSRVSP GIHIPCEVPT VRECEETENI
CGVILPDMIR CRSKPVSRRK RCEDHKGMRV NAFFFLLNPT ERDKAVNEDK SKPETSTGMN
QEGSGLLCEA TTKNGLPCTR SAPEGSKRCW QHKDKTLNHG SSENVQSATA SQVICGFKLY
NGSVCEKSPV KGRKRCEEHK GMRITS
