ETA2_SCHPO
ID ETA2_SCHPO Reviewed; 569 AA.
AC O14108; Q10590;
DT 01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 132.
DE RecName: Full=DNA-binding protein eta2;
GN Name=eta2; ORFNames=SPAC31G5.10;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=CD16-1;
RX PubMed=12597277; DOI=10.1093/dnares/9.6.209;
RA Watanabe T., Miyashita K., Saito T.T., Nabeshima K., Nojima H.;
RT "Abundant poly(A)-bearing RNAs that lack open reading frames in
RT Schizosaccharomyces pombe.";
RL DNA Res. 9:209-215(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR EMBL; AB084881; BAC54905.1; -; mRNA.
DR EMBL; CU329670; CAB11694.1; -; Genomic_DNA.
DR PIR; T38627; T38627.
DR RefSeq; NP_594010.1; NM_001019436.1.
DR AlphaFoldDB; O14108; -.
DR SMR; O14108; -.
DR BioGRID; 279031; 6.
DR STRING; 4896.SPAC31G5.10.1; -.
DR iPTMnet; O14108; -.
DR PaxDb; O14108; -.
DR PRIDE; O14108; -.
DR EnsemblFungi; SPAC31G5.10.1; SPAC31G5.10.1:pep; SPAC31G5.10.
DR GeneID; 2542575; -.
DR KEGG; spo:SPAC31G5.10; -.
DR PomBase; SPAC31G5.10; eta2.
DR VEuPathDB; FungiDB:SPAC31G5.10; -.
DR eggNOG; KOG0051; Eukaryota.
DR HOGENOM; CLU_483250_0_0_1; -.
DR InParanoid; O14108; -.
DR OMA; YMRAIFE; -.
DR PhylomeDB; O14108; -.
DR PRO; PR:O14108; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0043565; F:sequence-specific DNA binding; ISO:PomBase.
DR GO; GO:0006363; P:termination of RNA polymerase I transcription; ISO:PomBase.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 3.
DR SUPFAM; SSF46689; SSF46689; 2.
DR PROSITE; PS50090; MYB_LIKE; 2.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat.
FT CHAIN 1..569
FT /note="DNA-binding protein eta2"
FT /id="PRO_0000197087"
FT DOMAIN 322..371
FT /note="Myb-like 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00133"
FT DOMAIN 377..459
FT /note="Myb-like 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00133"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 133..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 459..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 21
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 569 AA; 65282 MW; B4FFEF9999D8FF9E CRC64;
MMLAIDMTIN ENQGTRSNLE SPTLSCSSKG AMQERDVMFT DHNTFNITNN KSRPGSLMKS
MKRKDVYEFD EDNEFEFEMG SLIHKPSRAH SLGGTSEPVS DDHKDCMEAT RQLLENSPLS
SVVVKTCSDH ASKRKIARSS SDDSESKVES TNSFNAKKRK DAWTEEHEKW FQARIDELLT
IRSISREQMI EILEDEHAGS RLQGFLESVA SFLNRKENSL LKYMRAFFQV AGYEKIDIGS
LAAEEDSQLN FSLEDAQVIQ KVVLSYCNNE GVDLQEFGFR MSSSSLRHTN INFLYNELRE
LLPTSISRKG IIRYLKEIYK PLDPKDRNAW EESELKKLYT LVEQEGTRWN SIANKLGTSP
AACMSQWRFV VGTSTQETID RRKLWTNEEE AKLLDLVKSS YRSSFHTKKM TSLFTHNNHT
TSNIQREIPA SDSIAWHSIS KKLGTKSPES CRKQYEKTIA SYSSNQRQEE DQGKKRKKRK
KKKSKGKRKF YVADSLKLLE HVQRQCGEAI SINAIDWKGI VKQMPKWSEE ELRAQATNLV
ASVRGWKKTR LSESVRIAIT DLKSLPPDV
