ID   ETC1_ARATH              Reviewed;          83 AA.
AC   Q9LNI5;
DT   24-JUL-2013, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 157.
DE   RecName: Full=MYB-like transcription factor ETC1;
DE   AltName: Full=Protein ENHANCER OF TRY AND CPC 1;
GN   Name=ETC1; OrderedLocusNames=At1g01380; ORFNames=F6F3.18;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Qu L., Gu H.;
RT   "The MYB transcription factor family in Arabidopsis: a genome-wide cloning
RT   and expression pattern analysis.";
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [4]
RP   FUNCTION, AND TISSUE SPECIFICITY.
RX   PubMed=15063185; DOI=10.1016/j.ydbio.2003.12.037;
RA   Kirik V., Simon M., Huelskamp M., Schiefelbein J.;
RT   "The ENHANCER OF TRY AND CPC1 gene acts redundantly with TRIPTYCHON and
RT   CAPRICE in trichome and root hair cell patterning in Arabidopsis.";
RL   Dev. Biol. 268:506-513(2004).
RN   [5]
RP   FUNCTION, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RX   PubMed=15584952; DOI=10.1111/j.1365-313x.2004.02259.x;
RA   Esch J.J., Chen M.A., Hillestad M., Marks M.D.;
RT   "Comparison of TRY and the closely related At1g01380 gene in controlling
RT   Arabidopsis trichome patterning.";
RL   Plant J. 40:860-869(2004).
CC   -!- FUNCTION: MYB-type transcription factor involved in epidermal cell fate
CC       specification. Acts as a negative regulator of trichome development, by
CC       mediating lateral inhibition. Promotes the formation of hair developing
CC       cells in H position in root epidermis, probably by inhibiting non-hair
CC       cell formation. {ECO:0000269|PubMed:15063185,
CC       ECO:0000269|PubMed:15584952}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15584952}.
CC   -!- TISSUE SPECIFICITY: Expressed in developing trichomes and non-root hair
CC       cells. {ECO:0000269|PubMed:15063185, ECO:0000269|PubMed:15584952}.
CC   -!- MISCELLANEOUS: Overexpression of ETC1 results in the suppression of
CC       trichomes and overproduction of root hairs, as observed for CPC, TRY,
CC       ETC2 and ETC3. {ECO:0000305|PubMed:15063185}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY519518; AAS09988.1; -; mRNA.
DR   EMBL; AC023628; AAF97342.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE27280.1; -; Genomic_DNA.
DR   PIR; C86144; C86144.
DR   RefSeq; NP_171645.1; NM_100020.4.
DR   AlphaFoldDB; Q9LNI5; -.
DR   SMR; Q9LNI5; -.
DR   BioGRID; 23336; 7.
DR   IntAct; Q9LNI5; 3.
DR   STRING; 3702.AT1G01380.1; -.
DR   PaxDb; Q9LNI5; -.
DR   PRIDE; Q9LNI5; -.
DR   EnsemblPlants; AT1G01380.1; AT1G01380.1; AT1G01380.
DR   GeneID; 838096; -.
DR   Gramene; AT1G01380.1; AT1G01380.1; AT1G01380.
DR   KEGG; ath:AT1G01380; -.
DR   Araport; AT1G01380; -.
DR   TAIR; locus:2035287; AT1G01380.
DR   eggNOG; ENOG502R1NM; Eukaryota.
DR   HOGENOM; CLU_178021_1_0_1; -.
DR   InParanoid; Q9LNI5; -.
DR   OMA; MKNHRRS; -.
DR   OrthoDB; 1531077at2759; -.
DR   PhylomeDB; Q9LNI5; -.
DR   PRO; PR:Q9LNI5; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9LNI5; baseline and differential.
DR   Genevisible; Q9LNI5; AT.
DR   GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR   GO; GO:1900033; P:negative regulation of trichome patterning; IGI:UniProtKB.
DR   GO; GO:0080147; P:root hair cell development; IGI:UniProtKB.
DR   CDD; cd00167; SANT; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017930; Myb_dom.
DR   InterPro; IPR001005; SANT/Myb.
DR   Pfam; PF00249; Myb_DNA-binding; 1.
DR   SMART; SM00717; SANT; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; DNA-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..83
FT                   /note="MYB-like transcription factor ETC1"
FT                   /id="PRO_0000423052"
FT   DOMAIN          35..72
FT                   /note="Myb-like"
SQ   SEQUENCE   83 AA;  9831 MW;  3D4802F360042860 CRC64;
     MNTQRKSKHL KTNPTIVASS SEEVSSLEWE EIAMAQEEED LICRMYKLVG ERWDLIAGRI
     PGRTAEEIER FWVMKNHRRS QLR