ETFB_ANAPI
ID ETFB_ANAPI Reviewed; 267 AA.
AC G3KIM7;
DT 13-NOV-2013, integrated into UniProtKB/Swiss-Prot.
DT 16-NOV-2011, sequence version 1.
DT 03-AUG-2022, entry version 31.
DE RecName: Full=Acryloyl-CoA reductase electron transfer subunit gamma;
DE AltName: Full=Electron transfer flavoprotein small subunit;
DE Short=ETFSS;
DE AltName: Full=Electron transfer flavoprotein subunit gamma;
DE Short=Gamma-ETF;
GN Name=acrB;
OS Anaerotignum propionicum (Clostridium propionicum).
OC Bacteria; Firmicutes; Clostridia; Eubacteriales; Lachnospiraceae;
OC Anaerotignum.
OX NCBI_TaxID=28446;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 25522 / DSM 1682 / JCM 1430 / NCIMB 10656 / VPI 5303 / X2;
RA Poehlein A., Schlien K., Daniel R., Gottschalk G., Buckel W.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 25522 / DSM 1682 / JCM 1430 / NCIMB 10656 / VPI 5303 / X2;
RX PubMed=22810300; DOI=10.1007/s00253-012-4274-y;
RA Kandasamy V., Vaidyanathan H., Djurdjevic I., Jayamani E.,
RA Ramachandran K.B., Buckel W., Jayaraman G., Ramalingam S.;
RT "Engineering Escherichia coli with acrylate pathway genes for propionic
RT acid synthesis and its impact on mixed-acid fermentation.";
RL Appl. Microbiol. Biotechnol. 97:1191-1200(2013).
RN [3]
RP FUNCTION, SUBCELLULAR LOCATION, MASS SPECTROMETRY, AND SUBUNIT.
RC STRAIN=ATCC 25522 / DSM 1682 / JCM 1430 / NCIMB 10656 / VPI 5303 / X2;
RX PubMed=12603323; DOI=10.1046/j.1432-1033.2003.03450.x;
RA Hetzel M., Brock M., Selmer T., Pierik A.J., Golding B.T., Buckel W.;
RT "Acryloyl-CoA reductase from Clostridium propionicum. An enzyme complex of
RT propionyl-CoA dehydrogenase and electron-transferring flavoprotein.";
RL Eur. J. Biochem. 270:902-910(2003).
CC -!- FUNCTION: Part of the ETF-acryloyl-CoA reductase complex involved in
CC the pathway of L-alanine fermentation. The electron transfer
CC flavoprotein (ETF) serves as a specific electron acceptor for acryloyl-
CC CoA reductase. {ECO:0000269|PubMed:12603323}.
CC -!- SUBUNIT: Heterohexadecamer; tetramer of tetramers. Each tetramer is
CC composed of 2 alpha (AcrC), a beta (AcrA) and a gamma (AcrB) subunit.
CC {ECO:0000269|PubMed:12603323}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12603323}.
CC -!- MASS SPECTROMETRY: Mass=28450; Method=MALDI;
CC Evidence={ECO:0000269|PubMed:12603323};
CC -!- SIMILARITY: Belongs to the ETF beta-subunit/FixA family. {ECO:0000305}.
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DR EMBL; JN244655; AEM62997.1; -; Genomic_DNA.
DR AlphaFoldDB; G3KIM7; -.
DR SMR; G3KIM7; -.
DR PRIDE; G3KIM7; -.
DR BioCyc; MetaCyc:MON-12759; -.
DR SABIO-RK; G3KIM7; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR CDD; cd01714; ETF_beta; 1.
DR Gene3D; 3.40.50.620; -; 1.
DR InterPro; IPR014730; ETF_a/b_N.
DR InterPro; IPR012255; ETF_b.
DR InterPro; IPR033948; ETF_beta_N.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR21294; PTHR21294; 1.
DR Pfam; PF01012; ETF; 1.
DR PIRSF; PIRSF000090; Beta-ETF; 1.
DR SMART; SM00893; ETF; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Electron transport; Transport.
FT CHAIN 1..267
FT /note="Acryloyl-CoA reductase electron transfer subunit
FT gamma"
FT /id="PRO_0000424269"
SQ SEQUENCE 267 AA; 28852 MW; FFE24D9F747A079B CRC64;
MRIYVCVKQV PDTSGKVAVN PDGTLNRASM AAIINPDDMS AIEQALKLKD ETGCQVTALT
MGPPPAEGML REIIAMGADD GVLISAREFG GSDTFATSQI ISAAIHKLGL SNEDMIFCGR
QAIDGDTAQV GPQIAEKLSI PQVTYGAGIK KSGDLVLVKR MLEDGYMMIE VETPCLITCI
QDKAVKPRYM TLNGIMECYS KPLLVLDYEA LKDEPLIELD TIGLKGSPTN IFKSFTPPQK
GVGVMLQGTD KEKVEDLVDK LMQKHVI
