ID   ETFB_DICDI              Reviewed;         250 AA.
AC   Q54YZ4;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Electron transfer flavoprotein subunit beta;
DE            Short=Beta-ETF;
GN   Name=etfb; ORFNames=DDB_G0277991;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: The electron transfer flavoprotein serves as a specific
CC       electron acceptor for several dehydrogenases, including five acyl-CoA
CC       dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers
CC       the electrons to the main mitochondrial respiratory chain via ETF-
CC       ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
CC       {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
CC       Note=Binds 1 FAD per dimer. {ECO:0000250};
CC   -!- COFACTOR:
CC       Name=AMP; Xref=ChEBI:CHEBI:456215; Evidence={ECO:0000250};
CC       Note=Binds 1 AMP per subunit. {ECO:0000250};
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta subunit. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ETF beta-subunit/FixA family. {ECO:0000305}.
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DR   EMBL; AAFI02000023; EAL68168.1; -; Genomic_DNA.
DR   RefSeq; XP_642058.1; XM_636966.1.
DR   AlphaFoldDB; Q54YZ4; -.
DR   SMR; Q54YZ4; -.
DR   STRING; 44689.DDB0267018; -.
DR   PaxDb; Q54YZ4; -.
DR   EnsemblProtists; EAL68168; EAL68168; DDB_G0277991.
DR   GeneID; 8621270; -.
DR   KEGG; ddi:DDB_G0277991; -.
DR   dictyBase; DDB_G0277991; etfb.
DR   eggNOG; KOG3180; Eukaryota.
DR   HOGENOM; CLU_060196_0_0_1; -.
DR   InParanoid; Q54YZ4; -.
DR   OMA; YNGGMVP; -.
DR   PhylomeDB; Q54YZ4; -.
DR   Reactome; R-DDI-611105; Respiratory electron transport.
DR   PRO; PR:Q54YZ4; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
DR   GO; GO:0009055; F:electron transfer activity; IBA:GO_Central.
DR   CDD; cd01714; ETF_beta; 1.
DR   Gene3D; 3.40.50.620; -; 1.
DR   InterPro; IPR000049; ET-Flavoprotein_bsu_CS.
DR   InterPro; IPR014730; ETF_a/b_N.
DR   InterPro; IPR012255; ETF_b.
DR   InterPro; IPR033948; ETF_beta_N.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR21294; PTHR21294; 1.
DR   Pfam; PF01012; ETF; 1.
DR   PIRSF; PIRSF000090; Beta-ETF; 1.
DR   SMART; SM00893; ETF; 1.
DR   PROSITE; PS01065; ETF_BETA; 1.
PE   3: Inferred from homology;
KW   Electron transport; FAD; Flavoprotein; Mitochondrion; Reference proteome;
KW   Transport.
FT   CHAIN           1..250
FT                   /note="Electron transfer flavoprotein subunit beta"
FT                   /id="PRO_0000328129"
SQ   SEQUENCE   250 AA;  27473 MW;  83769AFD3B3CDF4F CRC64;
     MSLKILVPIK RVVDYAVKIR VKGDKSGVET ANVKMSMNPF DEIAVEEAIR IKEKNLAKEI
     IAVSMGPKTS QETIRTAIAM GADKGIHVET TAELQPLSVA KLLKELVDKE KPNLIILGKQ
     AIDDDCNQTA QMLAGLLNWP QATFASKVDI KDDSVHVTRE IDGGLETLSM KLPAIISCDL
     RLNEPRYAKL QNIMKSKKAE LKVETPESLN VDTNCNLKII SVEEPPKRSG GVKVESVENV
     VEALKKHALI