ETFB_MYCLE
ID ETFB_MYCLE Reviewed; 266 AA.
AC O33095;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 112.
DE RecName: Full=Electron transfer flavoprotein subunit beta;
DE Short=Beta-ETF;
DE AltName: Full=Electron transfer flavoprotein small subunit;
DE Short=ETFSS;
GN Name=etfB; Synonyms=fixA; OrderedLocusNames=ML1712; ORFNames=MLCB637.03;
OS Mycobacterium leprae (strain TN).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=272631;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TN;
RX PubMed=11234002; DOI=10.1038/35059006;
RA Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA Barrell B.G.;
RT "Massive gene decay in the leprosy bacillus.";
RL Nature 409:1007-1011(2001).
CC -!- FUNCTION: The electron transfer flavoprotein serves as a specific
CC electron acceptor for other dehydrogenases. It transfers the electrons
CC to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF
CC dehydrogenase) (By similarity). {ECO:0000250}.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
CC Note=Binds 1 FAD per dimer. {ECO:0000250};
CC -!- COFACTOR:
CC Name=AMP; Xref=ChEBI:CHEBI:456215; Evidence={ECO:0000250};
CC Note=Binds 1 AMP per subunit. {ECO:0000250};
CC -!- SUBUNIT: Heterodimer of an alpha and a beta subunit.
CC -!- SIMILARITY: Belongs to the ETF beta-subunit/FixA family. {ECO:0000305}.
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DR EMBL; Z99263; CAB16418.1; -; Genomic_DNA.
DR EMBL; AL583923; CAC30665.1; -; Genomic_DNA.
DR PIR; T45396; T45396.
DR RefSeq; NP_302179.1; NC_002677.1.
DR RefSeq; WP_010908500.1; NC_002677.1.
DR AlphaFoldDB; O33095; -.
DR SMR; O33095; -.
DR STRING; 272631.ML1712; -.
DR EnsemblBacteria; CAC30665; CAC30665; CAC30665.
DR KEGG; mle:ML1712; -.
DR PATRIC; fig|272631.5.peg.3225; -.
DR Leproma; ML1712; -.
DR eggNOG; COG2086; Bacteria.
DR HOGENOM; CLU_060196_2_0_11; -.
DR OMA; YNGGMVP; -.
DR Proteomes; UP000000806; Chromosome.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR CDD; cd01714; ETF_beta; 1.
DR Gene3D; 3.40.50.620; -; 1.
DR InterPro; IPR000049; ET-Flavoprotein_bsu_CS.
DR InterPro; IPR014730; ETF_a/b_N.
DR InterPro; IPR012255; ETF_b.
DR InterPro; IPR033948; ETF_beta_N.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR21294; PTHR21294; 1.
DR Pfam; PF01012; ETF; 1.
DR PIRSF; PIRSF000090; Beta-ETF; 1.
DR SMART; SM00893; ETF; 1.
DR PROSITE; PS01065; ETF_BETA; 1.
PE 3: Inferred from homology;
KW Electron transport; FAD; Flavoprotein; Reference proteome; Transport.
FT CHAIN 1..266
FT /note="Electron transfer flavoprotein subunit beta"
FT /id="PRO_0000167881"
SQ SEQUENCE 266 AA; 28160 MW; C0347643A05AEBCD CRC64;
MTNIVVLIKQ VPDTWSERKL TDGDFTLDRE AADAVLDEIN ERAVEEALQI REKEAVDGIK
GSVTVLTAGP ERATEAIRKA LSMGADKAVH LKDDGMHGSD VIQTGWALAR ALGTIEGTEL
VIAGNESTDG VGGVVPAIIA EYLGLPQLTH LRTISVEGGK ITGERETDEG VFTLEAVLPA
VVSVNEKINE PRFPSFKGIM AAKKKEVTVL TLAEIGVEVD EVGLANAGSK VLVSTPKPAK
TAGEKITDEG DGGNQIVQYL VAQKII
