ETFR1_BOVIN
ID ETFR1_BOVIN Reviewed; 88 AA.
AC Q0VCR0;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=Electron transfer flavoprotein regulatory factor 1 {ECO:0000250|UniProtKB:Q6IPR1};
DE AltName: Full=LYR motif-containing protein 5 {ECO:0000250|UniProtKB:Q6IPR1};
GN Name=ETFRF1 {ECO:0000250|UniProtKB:Q6IPR1};
GN Synonyms=LYRM5 {ECO:0000250|UniProtKB:Q6IPR1};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Fetal pons;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts as a regulator of the electron transfer flavoprotein by
CC promoting the removal of flavin from the ETF holoenzyme (composed of
CC ETFA and ETFB). {ECO:0000250|UniProtKB:Q6IPR1}.
CC -!- SUBUNIT: homotetramer. Interacts with NDUFAB1. Interacts with ETFA.
CC Interacts with ETFB. {ECO:0000250|UniProtKB:Q6IPR1}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q6IPR1}.
CC -!- SIMILARITY: Belongs to the complex I LYR family. {ECO:0000305}.
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DR EMBL; BC120046; AAI20047.1; -; mRNA.
DR RefSeq; NP_001108332.1; NM_001114860.2.
DR AlphaFoldDB; Q0VCR0; -.
DR SMR; Q0VCR0; -.
DR STRING; 9913.ENSBTAP00000037736; -.
DR PaxDb; Q0VCR0; -.
DR PRIDE; Q0VCR0; -.
DR Ensembl; ENSBTAT00000037914; ENSBTAP00000037736; ENSBTAG00000026624.
DR Ensembl; ENSBTAT00000084016; ENSBTAP00000064654; ENSBTAG00000026624.
DR GeneID; 783110; -.
DR KEGG; bta:783110; -.
DR CTD; 144363; -.
DR VEuPathDB; HostDB:ENSBTAG00000026624; -.
DR VGNC; VGNC:28622; ETFRF1.
DR eggNOG; ENOG502S4S4; Eukaryota.
DR GeneTree; ENSGT00390000001810; -.
DR HOGENOM; CLU_141157_2_0_1; -.
DR InParanoid; Q0VCR0; -.
DR OMA; PQGYDYF; -.
DR OrthoDB; 1606295at2759; -.
DR TreeFam; TF300251; -.
DR Proteomes; UP000009136; Chromosome 5.
DR Bgee; ENSBTAG00000026624; Expressed in cardiac atrium and 106 other tissues.
DR GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR GO; GO:0022904; P:respiratory electron transport chain; ISS:UniProtKB.
DR CDD; cd20265; Complex1_LYR_ETFRF1_LYRM5; 1.
DR InterPro; IPR008011; Complex1_LYR_dom.
DR InterPro; IPR045296; Complex1_LYR_ETFRF1_LYRM5.
DR Pfam; PF05347; Complex1_LYR; 1.
PE 3: Inferred from homology;
KW Mitochondrion; Reference proteome.
FT CHAIN 1..88
FT /note="Electron transfer flavoprotein regulatory factor 1"
FT /id="PRO_0000313022"
SQ SEQUENCE 88 AA; 10705 MW; 4FE35E94E1C5F361 CRC64;
MANSLRGEVL NLYKNLLYLG RDYPKGADYF KRRLKNVFLK NKDVKDPEKI KELIERGKFV
MKELEALYFL RKYRAMKQRY YSDTNKTK