ETIF1_ANOGA
ID ETIF1_ANOGA Reviewed; 110 AA.
AC P42678; Q7Q5F8;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 25-MAY-2022, entry version 111.
DE RecName: Full=Eukaryotic translation initiation factor eIF1 {ECO:0000250|UniProtKB:Q9VZS3};
DE AltName: Full=Protein translation factor SUI1 homolog {ECO:0000250|UniProtKB:Q9VZS3};
GN Name=eIF1 {ECO:0000250|UniProtKB:Q9VZS3}; ORFNames=AGAP006459;
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=G3;
RX PubMed=8163206; DOI=10.1016/0378-1119(94)90589-4;
RA Besansky N.J., Hamm D.M., Collins F.H.;
RT "An Anopheles gambiae cDNA predicts a protein similar to a yeast Sui1
RT translation factor.";
RL Gene 141:299-300(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST;
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
CC -!- FUNCTION: Probably involved in translation.
CC -!- SIMILARITY: Belongs to the SUI1 family. {ECO:0000305}.
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DR EMBL; U02588; AAA18901.1; -; mRNA.
DR EMBL; AAAB01008960; EAA11885.2; -; Genomic_DNA.
DR RefSeq; XP_316499.2; XM_316499.4.
DR AlphaFoldDB; P42678; -.
DR SMR; P42678; -.
DR STRING; 7165.AGAP006459-PA; -.
DR PaxDb; P42678; -.
DR GeneID; 1277069; -.
DR KEGG; aga:AgaP_AGAP006459; -.
DR CTD; 1277069; -.
DR VEuPathDB; VectorBase:AGAP006459; -.
DR eggNOG; KOG1770; Eukaryota.
DR HOGENOM; CLU_082805_3_2_1; -.
DR InParanoid; P42678; -.
DR OMA; VENHIHI; -.
DR OrthoDB; 1493146at2759; -.
DR PhylomeDB; P42678; -.
DR Proteomes; UP000007062; Chromosome 2L.
DR GO; GO:0016282; C:eukaryotic 43S preinitiation complex; IBA:GO_Central.
DR GO; GO:0043024; F:ribosomal small subunit binding; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR CDD; cd11566; eIF1_SUI1; 1.
DR InterPro; IPR001950; SUI1.
DR InterPro; IPR036877; SUI1_dom_sf.
DR InterPro; IPR005874; SUI1_euk.
DR Pfam; PF01253; SUI1; 1.
DR PIRSF; PIRSF004499; SUI1_euk; 1.
DR SUPFAM; SSF55159; SSF55159; 1.
DR TIGRFAMs; TIGR01160; SUI1_MOF2; 1.
DR PROSITE; PS50296; SUI1; 1.
PE 3: Inferred from homology;
KW Protein biosynthesis; Reference proteome; Translation regulation.
FT CHAIN 1..110
FT /note="Eukaryotic translation initiation factor eIF1"
FT /id="PRO_0000130562"
SQ SEQUENCE 110 AA; 12418 MW; ACC5DC26A6FECE02 CRC64;
MSIQNLNTFD PFADAIKGAD YDVQDGLVHI RIQQRNGRKT LTTVQGLSAE YDLKKIVRAC
KKEFACNGTV IEHPEYGEVL QLQGDQRENI CQWLTKSGLA KPEQLKVHGF