ID   ETT1_CANDC              Reviewed;         420 AA.
AC   B9WAV2;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   24-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Enhancer of translation termination 1;
GN   Name=ETT1; ORFNames=CD36_17450;
OS   Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 /
OS   NRRL Y-17841) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=573826;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841;
RX   PubMed=19745113; DOI=10.1101/gr.097501.109;
RA   Jackson A.P., Gamble J.A., Yeomans T., Moran G.P., Saunders D., Harris D.,
RA   Aslett M., Barrell J.F., Butler G., Citiulo F., Coleman D.C.,
RA   de Groot P.W.J., Goodwin T.J., Quail M.A., McQuillan J., Munro C.A.,
RA   Pain A., Poulter R.T., Rajandream M.A., Renauld H., Spiering M.J.,
RA   Tivey A., Gow N.A.R., Barrell B., Sullivan D.J., Berriman M.;
RT   "Comparative genomics of the fungal pathogens Candida dubliniensis and
RT   Candida albicans.";
RL   Genome Res. 19:2231-2244(2009).
CC   -!- FUNCTION: Required for correct translation termination and probably
CC       involved in regulation of hypoxic gene expression. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ETT1 family. {ECO:0000305}.
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DR   EMBL; FM992689; CAX43522.1; -; Genomic_DNA.
DR   RefSeq; XP_002418222.1; XM_002418177.1.
DR   AlphaFoldDB; B9WAV2; -.
DR   SMR; B9WAV2; -.
DR   STRING; 42374.XP_002418222.1; -.
DR   EnsemblFungi; CAX43522; CAX43522; CD36_17450.
DR   GeneID; 8045782; -.
DR   KEGG; cdu:CD36_17450; -.
DR   CGD; CAL0000167204; Cd36_17450.
DR   eggNOG; ENOG502QPHX; Eukaryota.
DR   HOGENOM; CLU_050427_0_0_1; -.
DR   OrthoDB; 1255094at2759; -.
DR   Proteomes; UP000002605; Chromosome 2.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   InterPro; IPR024318; Nro1/ETT1.
DR   PANTHER; PTHR28290; PTHR28290; 1.
DR   Pfam; PF12753; Nro1; 1.
PE   3: Inferred from homology;
KW   Nucleus; Transcription; Transcription regulation; Translation regulation.
FT   CHAIN           1..420
FT                   /note="Enhancer of translation termination 1"
FT                   /id="PRO_0000406612"
FT   REGION          1..41
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          227..256
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..30
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        235..252
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   420 AA;  48445 MW;  8A009591CBEB2002 CRC64;
     MAKRTLGLAK AAKAKKQKKE QVHQESSDEE SSSENQLTIE LPEEIDANDE ISQLKGLHKT
     YLESERDNEL LVNGLIHECD RLLRENDTEN KSPLPPVFHA IYATALAELS KFHTEELDKV
     KEYFTAALER VELGLQQNPN DITLLVTKTK ILLDQISLQY IAPLTLESDT KELDREIDEL
     LDATLSVYES VEARAKELND YSIFDDFETL DILEALDDIL DIVDNFGRKN QGDDDSDEND
     DDDEDEEEES VELSENHPLY KIKNSDKYDQ WWRDHTHLYL DNLEKLENGS SELKREVCQR
     LGQSYLQESE VPYSVFTTLK YDDEYDGIEE LEGLTEKQAQ EISQELITKA LDYLKRAKDE
     EDPETWVGIA EAMISLGNLY EVDSKQQDDL YVEAEKILKK ANNVTNGKFK EELDNLLYKE