ID   ETT1_CANGA              Reviewed;         404 AA.
AC   Q6FKN4;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Enhancer of translation termination 1;
GN   Name=ETT1; OrderedLocusNames=CAGL0L10164g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for correct translation termination and probably
CC       involved in regulation of hypoxic gene expression. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ETT1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR380958; CAG62184.1; -; Genomic_DNA.
DR   RefSeq; XP_449210.1; XM_449210.1.
DR   AlphaFoldDB; Q6FKN4; -.
DR   SMR; Q6FKN4; -.
DR   STRING; 5478.XP_449210.1; -.
DR   EnsemblFungi; CAG62184; CAG62184; CAGL0L10164g.
DR   GeneID; 2891060; -.
DR   KEGG; cgr:CAGL0L10164g; -.
DR   CGD; CAL0135444; CAGL0L10164g.
DR   VEuPathDB; FungiDB:CAGL0L10164g; -.
DR   eggNOG; ENOG502QPHX; Eukaryota.
DR   HOGENOM; CLU_050427_0_0_1; -.
DR   InParanoid; Q6FKN4; -.
DR   OMA; GIVHECD; -.
DR   Proteomes; UP000002428; Chromosome L.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0006415; P:translational termination; IEA:EnsemblFungi.
DR   InterPro; IPR024318; Nro1/ETT1.
DR   PANTHER; PTHR28290; PTHR28290; 1.
DR   Pfam; PF12753; Nro1; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Transcription; Transcription regulation;
KW   Translation regulation.
FT   CHAIN           1..404
FT                   /note="Enhancer of translation termination 1"
FT                   /id="PRO_0000406613"
FT   REGION          1..34
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   404 AA;  45683 MW;  5E50F96757ACD6AA CRC64;
     MAKRPLGLGK QKQNKKTKVE SSSGEVSRES TPVASQIEVE LADDVDADDE LVQLKGLWQT
     YFDSDRDSEY VLNGIVHECD RLLREADKEG KIKELSDVFH AIYALALSEL TIFKAGEEED
     EKKKKEEIAQ FFDNALERCS LGESDCGKSD LLDLVKAKVI IQRVPLEHMS ALTVSSKSGL
     NLNTLVEDAK KHFKVSTKDL SLVYEVLEMF DDLLDITENF GHEEQIAEGL DSDDEEDLEP
     IQLDKKHPVY EMQQNLASNY KWLKEQLIAL LGQLNKKDHA KLYHLTAKKI GELYLKDAEE
     PTNVYLSLAY DDDESKQSSK DCKESQASAL KLVQNAIDYL DKAQIEDEPE TWAQVAEAYI
     DLGNLHDNES SEQEKAYQTA ETLLTKANTA THGKYDDILE NLKQ