ID   ETT1_CLAL4              Reviewed;         426 AA.
AC   C4YBG0;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=Enhancer of translation termination 1;
GN   Name=ETT1; ORFNames=CLUG_05538;
OS   Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Metschnikowiaceae; Clavispora.
OX   NCBI_TaxID=306902;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42720;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Required for correct translation termination and probably
CC       involved in regulation of hypoxic gene expression. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ETT1 family. {ECO:0000305}.
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DR   EMBL; CH408082; EEQ41410.1; -; Genomic_DNA.
DR   RefSeq; XP_002614760.1; XM_002614714.1.
DR   AlphaFoldDB; C4YBG0; -.
DR   SMR; C4YBG0; -.
DR   STRING; 306902.C4YBG0; -.
DR   EnsemblFungi; EEQ41410; EEQ41410; CLUG_05538.
DR   GeneID; 8495118; -.
DR   KEGG; clu:CLUG_05538; -.
DR   VEuPathDB; FungiDB:CLUG_05538; -.
DR   HOGENOM; CLU_050427_0_0_1; -.
DR   InParanoid; C4YBG0; -.
DR   OMA; GIVHECD; -.
DR   Proteomes; UP000007703; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   InterPro; IPR024318; Nro1/ETT1.
DR   PANTHER; PTHR28290; PTHR28290; 1.
DR   Pfam; PF12753; Nro1; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Transcription; Transcription regulation;
KW   Translation regulation.
FT   CHAIN           1..426
FT                   /note="Enhancer of translation termination 1"
FT                   /id="PRO_0000406615"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   426 AA;  48294 MW;  33A2C1E38F0650A8 CRC64;
     MAPKRPLGIG KAAKAKKQKK ESTENESVGE TAASNELTVE LDEEIEANDA VAQLKALWKT
     YFASEDKSEL MLNGIIHECD RILRKTHNTK EQDEDDEKIE LSGRFYAIYA LALSSLAFYH
     TEDLKKVNDF FAEAFDRIES GRKAFPDSVD LAFAEAKIMI SRIPLVEVSQ LLVDSRVGKE
     RSDVSKSLDA SLAKWEEAQK QAVAQNHFHH YNAENFDFLQ ALDDLLDMVD NFGQEIMEGE
     DSDAEEDEKP HVELDEGHPL FAIKSSDKYN LWWREQTIAF LDHLNKNIEN ASAKELPALA
     VLKRELCKRL GQSYLMEAEV PANVFTTLSY YSKDAKSLNG LTRVEAQKIS QDLFKRALTY
     LKQAQDEQEP ETWVNVAEAM ISLGNTYEID SKEQEETYKE AEAILVKANN ATNGKYEDIL
     ENLMQG