ID   ETT1_DEBHA              Reviewed;         443 AA.
AC   B5RTW5;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   04-NOV-2008, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Enhancer of translation termination 1;
GN   Name=ETT1; OrderedLocusNames=DEHA2E07106g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for correct translation termination and probably
CC       involved in regulation of hypoxic gene expression. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ETT1 family. {ECO:0000305}.
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DR   EMBL; CR382137; CAR65777.1; -; Genomic_DNA.
DR   RefSeq; XP_002770431.1; XM_002770385.1.
DR   AlphaFoldDB; B5RTW5; -.
DR   SMR; B5RTW5; -.
DR   STRING; 4959.XP_002770431.1; -.
DR   EnsemblFungi; CAR65777; CAR65777; DEHA2E07106g.
DR   GeneID; 8998689; -.
DR   KEGG; dha:DEHA2E07106g; -.
DR   VEuPathDB; FungiDB:DEHA2E07106g; -.
DR   eggNOG; ENOG502QPHX; Eukaryota.
DR   HOGENOM; CLU_050427_0_0_1; -.
DR   InParanoid; B5RTW5; -.
DR   OMA; GIVHECD; -.
DR   OrthoDB; 1255094at2759; -.
DR   Proteomes; UP000000599; Chromosome E.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   InterPro; IPR024318; Nro1/ETT1.
DR   PANTHER; PTHR28290; PTHR28290; 1.
DR   Pfam; PF12753; Nro1; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Transcription; Transcription regulation;
KW   Translation regulation.
FT   CHAIN           1..443
FT                   /note="Enhancer of translation termination 1"
FT                   /id="PRO_0000406616"
FT   REGION          1..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          86..107
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          241..261
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   443 AA;  50714 MW;  E694E4A3145E5D80 CRC64;
     MAPKRHLGLG KAAKSKKQKK DDSSEVENPV QQSNELTVEL NEEVDANDEV SQLRALWKTH
     AKSDKDNELV VNGIIHECDR LLRNSNLAEN EDGEDKNKAS TNEDGPKELP ADFHSIYALA
     LADLALFHST DVNKVKEFFD AALERVDLGL QSHTGSIELL FTKSRILINQ IPLQYISQLT
     VESKVQDGVP KIDEKLDAAL KIYEEAENQA KALKQYELFN EDNLEILQAF DDLLEIVDNF
     GKDNSEGDES DKEDDGDYEE EIQLSKKHPL YGIRNTDKYN EWWRDHTIQF LQNVDQQLEK
     LGISYKQENE TENALLPLRR EICKRIGQSY LQEAEIPSTV FTTLKYDEGF ADVDQLEGLT
     RDESQKISQY LFKTALDYLK MAEDKEEPES WVNIAESMIS LGNLYELDSE EQENYYTEAE
     KILTKANNAT NGKYEDILEN LQT