ID   ETT1_PICST              Reviewed;         440 AA.
AC   A3LUM8;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Enhancer of translation termination 1;
GN   Name=ETT1; ORFNames=PICST_58954;
OS   Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS   Y-11545) (Yeast) (Pichia stipitis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX   NCBI_TaxID=322104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX   PubMed=17334359; DOI=10.1038/nbt1290;
RA   Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA   Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA   Passoth V., Richardson P.M.;
RT   "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT   yeast Pichia stipitis.";
RL   Nat. Biotechnol. 25:319-326(2007).
CC   -!- FUNCTION: Required for correct translation termination and probably
CC       involved in regulation of hypoxic gene expression. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ETT1 family. {ECO:0000305}.
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DR   EMBL; CP000498; ABN66264.1; -; Genomic_DNA.
DR   RefSeq; XP_001384293.1; XM_001384256.1.
DR   AlphaFoldDB; A3LUM8; -.
DR   SMR; A3LUM8; -.
DR   STRING; 4924.XP_001384293.1; -.
DR   PRIDE; A3LUM8; -.
DR   EnsemblFungi; ABN66264; ABN66264; PICST_58954.
DR   GeneID; 4838409; -.
DR   KEGG; pic:PICST_58954; -.
DR   eggNOG; ENOG502QPHX; Eukaryota.
DR   HOGENOM; CLU_050427_0_0_1; -.
DR   InParanoid; A3LUM8; -.
DR   OMA; GIVHECD; -.
DR   OrthoDB; 1255094at2759; -.
DR   Proteomes; UP000002258; Chromosome 4.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   InterPro; IPR024318; Nro1/ETT1.
DR   PANTHER; PTHR28290; PTHR28290; 1.
DR   Pfam; PF12753; Nro1; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Transcription; Transcription regulation;
KW   Translation regulation.
FT   CHAIN           1..440
FT                   /note="Enhancer of translation termination 1"
FT                   /id="PRO_0000406622"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..35
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   440 AA;  50653 MW;  C992A728E1BB519C CRC64;
     MAKRSLGIGK ASKAKKQKSA PREEEKIEKD QATEGSNEIT VELNEEADAN DEIAQLKALW
     KTYNDSEKDN ELVINGIIHE CDRLLRNSKL GEEKEKEKEQ YTQELPDFFH SIYALALAEL
     AKFHTEDNKK VAEYFDAAVE RADLGLSQHQ DSIQLLFSKS KILLHQIALQ YISQLKVDTS
     ISKKVPKLSS YLDSALRTYE EAEKKADELK KYELFNADQL EILQVLDDLL DIVDNFGKDI
     AEGEDDDDEV EDDEIELEES HPLYAIRESD EYNQWWRDHI ILFLDNVDKH GKEIKVDFKE
     KAKSQEEEHP LLPLRREICK RIGQSYLQEA EVPSSVFTTL AYDDGFKNEK EINGLSLKES
     QKIAQKLIST ALKYLQWAED QEEPETWVNV AEAMISLGNL YEVESEEQES HYQEAEKILN
     KANNVTNGKY EDVLENLLGD