ID   ETT1_YEAS6              Reviewed;         412 AA.
AC   B5VRU9;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Enhancer of translation termination 1;
GN   Name=ETT1; ORFNames=AWRI1631_152110;
OS   Saccharomyces cerevisiae (strain AWRI1631) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=545124;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AWRI1631;
RX   PubMed=18778279; DOI=10.1111/j.1567-1364.2008.00434.x;
RA   Borneman A.R., Forgan A.H., Pretorius I.S., Chambers P.J.;
RT   "Comparative genome analysis of a Saccharomyces cerevisiae wine strain.";
RL   FEMS Yeast Res. 8:1185-1195(2008).
CC   -!- FUNCTION: Required for correct translation termination and probably
CC       involved in regulation of hypoxic gene expression in association TPA1.
CC       Inhibits replication of Brome mosaic virus (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with STM1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ETT1 family. {ECO:0000305}.
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DR   EMBL; ABSV01002138; EDZ69343.1; -; Genomic_DNA.
DR   AlphaFoldDB; B5VRU9; -.
DR   SMR; B5VRU9; -.
DR   Proteomes; UP000008988; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR024318; Nro1/ETT1.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR28290; PTHR28290; 1.
DR   Pfam; PF12753; Nro1; 1.
PE   3: Inferred from homology;
KW   Nucleus; Phosphoprotein; Transcription; Transcription regulation;
KW   Translation regulation.
FT   CHAIN           1..412
FT                   /note="Enhancer of translation termination 1"
FT                   /id="PRO_0000406627"
FT   REGION          1..45
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..32
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         30
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q08421"
SQ   SEQUENCE   412 AA;  47468 MW;  2988026AE800F282 CRC64;
     MAKRPLGLGK QSREKKRKVE SVEKKSDEPS RESTPVRSQM SVELDDDADL DDELAQLKGL
     WSKYFHSDRD DEYVLNGIVH ECDRLLRLSE EDKEIKKTLN DIFHGIYALA LSELTIFKAG
     DEEATEEKRK KDVSSFFENA IERVELGLSH FPESQFLKLV LAKIIFQRIP LEYISNLHLK
     SKDKKLDLVG QLEHGKKHFS IYENDTEFTF EILQMVNDLL DIVENFGREQ SIQEGIDSDN
     EEEEELIDIE LEPEHPVYPL QQSLEANYEW LRNHFDKLLD NTNTDMKIYA SIANTLGELY
     LKKAEEPSKV FLSLQYDDGS SKKVSDKEAK NVQETALKHT KKALEYLEKA KLEDDPDTWV
     QVAEAYIDLG NLLDNESAEQ EEAYKTAEEI LGKANKASHG KFQDVLDNFL QG