ID   ETT1_ZYGRC              Reviewed;         411 AA.
AC   C5DSC5;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 47.
DE   RecName: Full=Enhancer of translation termination 1;
GN   Name=ETT1; OrderedLocusNames=ZYRO0B15752g;
OS   Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568
OS   / NRRL Y-229) (Candida mogii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX   NCBI_TaxID=559307;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2623 / CBS 732 / BCRC 21506 / NBRC 1130 / NCYC 568 / NRRL
RC   Y-229;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Required for correct translation termination and probably
CC       involved in regulation of hypoxic gene expression. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ETT1 family. {ECO:0000305}.
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DR   EMBL; CU928174; CAR26686.1; -; Genomic_DNA.
DR   RefSeq; XP_002495619.1; XM_002495574.1.
DR   AlphaFoldDB; C5DSC5; -.
DR   SMR; C5DSC5; -.
DR   STRING; 559307.C5DSC5; -.
DR   EnsemblFungi; CAR26686; CAR26686; ZYRO0B15752g.
DR   GeneID; 8202793; -.
DR   KEGG; zro:ZYRO0B15752g; -.
DR   HOGENOM; CLU_050427_0_0_1; -.
DR   InParanoid; C5DSC5; -.
DR   Proteomes; UP000008536; Chromosome B.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   InterPro; IPR024318; Nro1/ETT1.
DR   PANTHER; PTHR28290; PTHR28290; 1.
DR   Pfam; PF12753; Nro1; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Transcription; Transcription regulation;
KW   Translation regulation.
FT   CHAIN           1..411
FT                   /note="Enhancer of translation termination 1"
FT                   /id="PRO_0000406630"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..23
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   411 AA;  47630 MW;  EDA58134144271A0 CRC64;
     MAKRALGLGQ KNKEKKRKVD NSNSNNEPNR NSPAPGADQI QVEMDENADL DDELTQLKGL
     WNNYFHSDRE SEYVLNGIIH ECDRLLRQSD SDEKTKKLLN DEFYAIYALA LSELTIFKTE
     QEGEDVSQYF DQALEWAEIG MEKTSKDSQL LQLAVSKIIL QRIPLQFISK LTVDSKPEDV
     NLDLFEQLQR AKKCFNVEKD LELAYEVLQM FDDLLDMLEN FGHGNNIDEG LDSDEEDEIE
     PVKLNKKHPL YRLQKAIPEN YAWLKETMVK LFENIEETTL RRNVARTLGH LFLKAAEEPT
     SVFMQQYDDE DEEEETEDKE VPKEIKQAQK EALSHTRTAL DYLEKAQVED EPETWVEVAE
     AYIDLGNLHD YQSSEQEKAY KVAEDILKKA NRASHGRFQD ILDNLLAKDQ D