ID   EUDIS_EUDSF             Reviewed;           5 AA.
AC   P86455;
DT   23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   23-MAR-2010, sequence version 1.
DT   10-FEB-2021, entry version 8.
DE   RecName: Full=Eudistomide {ECO:0000303|PubMed:19053188};
DE   AltName: Full=Eudistomide A {ECO:0000303|PubMed:19053188};
DE   AltName: Full=Eudistomide B {ECO:0000303|PubMed:19053188};
OS   Eudistoma sp. (strain FJ04-12-071).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Aplousobranchia;
OC   Polycitoridae; Eudistoma; unclassified Eudistoma.
OX   NCBI_TaxID=715217;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, MASS SPECTROMETRY, MYRISTOYLATION AT CYS-1, DISULFIDE
RP   BOND, AND METHYLATION AT CYS-5.
RX   PubMed=19053188; DOI=10.1021/jo8022582;
RA   Whitson E.L., Ratnayake A.S., Bugni T.S., Harper M.K., Ireland C.M.;
RT   "Isolation, structure elucidation, and synthesis of eudistomides A and B,
RT   lipopeptides from a Fijian ascidian Eudistoma sp.";
RL   J. Org. Chem. 74:1156-1162(2009).
CC   -!- PTM: Occurs in 2 forms which differ in the post-translational
CC       modification of Cys-1. In form Eudistomide A cysteine is modified to N-
CC       (12-oxomyristoyl)cysteine while in form Eudistomide B cysteine is
CC       modified to N-[(12R)-12-hydroxymyristoyl]cysteine (PubMed:19053188).
CC       {ECO:0000269|PubMed:19053188}.
CC   -!- MASS SPECTROMETRY: Mass=790.3897; Method=Electrospray; Note=The
CC       measured mass is that of Eudistomide A.;
CC       Evidence={ECO:0000269|PubMed:19053188};
CC   -!- MASS SPECTROMETRY: Mass=770.4160; Method=Electrospray; Note=The
CC       measured mass is that of Eudistomide B.;
CC       Evidence={ECO:0000269|PubMed:19053188};
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DR   iPTMnet; P86455; -.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Lipoprotein; Methylation;
KW   Myristate.
FT   PEPTIDE         1..5
FT                   /note="Eudistomide"
FT                   /evidence="ECO:0000269|PubMed:19053188"
FT                   /id="PRO_0000392633"
FT   MOD_RES         5
FT                   /note="Cysteine methyl ester"
FT                   /evidence="ECO:0000269|PubMed:19053188"
FT   LIPID           1
FT                   /note="N-(12-oxomyristoyl)cysteine; in form Eudistomide A"
FT                   /evidence="ECO:0000269|PubMed:19053188"
FT   LIPID           1
FT                   /note="N-[(12R)-12-hydroxymyristoyl]cysteine; in form
FT                   Eudistomide B"
FT                   /evidence="ECO:0000269|PubMed:19053188"
FT   DISULFID        1..5
FT                   /evidence="ECO:0000269|PubMed:19053188"
SQ   SEQUENCE   5 AA;  532 MW;  6EB737776ED00000 CRC64;
     CPPLC