ID   EURL_DANRE              Reviewed;         277 AA.
AC   Q503Y8;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Protein EURL homolog {ECO:0000305};
GN   Name=eurl {ECO:0000250|UniProtKB:Q9I8W6}; ORFNames=zgc:110006;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in cortical progenitor cell proliferation and
CC       differentiation. May promote dendritic spine development of post-
CC       migratory cortical projection neurons by modulating the beta-catenin
CC       signaling pathway. {ECO:0000250|UniProtKB:Q9D7G4}.
CC   -!- SIMILARITY: Belongs to the EURL family. {ECO:0000305}.
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DR   EMBL; BC095124; AAH95124.1; -; mRNA.
DR   RefSeq; NP_001018388.1; NM_001020552.1.
DR   AlphaFoldDB; Q503Y8; -.
DR   SMR; Q503Y8; -.
DR   STRING; 7955.ENSDARP00000109773; -.
DR   PaxDb; Q503Y8; -.
DR   Ensembl; ENSDART00000049633; ENSDARP00000049632; ENSDARG00000030803.
DR   Ensembl; ENSDART00000192734; ENSDARP00000157111; ENSDARG00000030803.
DR   GeneID; 553573; -.
DR   KEGG; dre:553573; -.
DR   ZFIN; ZDB-GENE-050522-119; zgc:110006.
DR   eggNOG; ENOG502QS2B; Eukaryota.
DR   GeneTree; ENSGT00390000002429; -.
DR   HOGENOM; CLU_059941_0_0_1; -.
DR   InParanoid; Q503Y8; -.
DR   OMA; PWLQIGR; -.
DR   OrthoDB; 1172773at2759; -.
DR   PhylomeDB; Q503Y8; -.
DR   TreeFam; TF331712; -.
DR   PRO; PR:Q503Y8; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 10.
DR   Bgee; ENSDARG00000030803; Expressed in mature ovarian follicle and 20 other tissues.
DR   ExpressionAtlas; Q503Y8; baseline.
DR   GO; GO:0021895; P:cerebral cortex neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0060999; P:positive regulation of dendritic spine development; ISS:UniProtKB.
DR   InterPro; IPR009704; EURL_prot.
DR   PANTHER; PTHR15961; PTHR15961; 1.
DR   Pfam; PF06937; EURL; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Differentiation; Neurogenesis; Reference proteome.
FT   CHAIN           1..277
FT                   /note="Protein EURL homolog"
FT                   /id="PRO_0000360429"
FT   REGION          173..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          197..229
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        181..201
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   277 AA;  31708 MW;  6CC44F6621F1FDE0 CRC64;
     MEEEEHFVNI DLNDDNICSI CKLETDTGTL SFCHVCFELS IEGISSATLL HSKSLRGHRD
     CFEKYHLIAN QKLSRAKASH STYEGVKRAL SQRINRIIQY AQNRDSVTPE NPGRWGAKQI
     LCHTQQAGRK LVPQSDAQVP RYAPRWTEEA SMVSESDYGK SMLDCHSAEE LGLGLWPGER
     PQNREQRDSR QRRHSGHSRE ELMRKNVEEL RQLNEQLLLQ IQNVFEELSV VVQEKDSLSS
     ELHVRHIAIE QLFKNCAKLP WLQIGRAGVK AANNPVE