ID   AGT2L_CAEEL             Reviewed;         467 AA.
AC   P91408;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   03-AUG-2022, entry version 148.
DE   RecName: Full=Ethanolamine-phosphate phospho-lyase homolog 1 {ECO:0000312|WormBase:T01B11.2a};
DE            EC=4.2.3.- {ECO:0000305};
DE   AltName: Full=Alanine--glyoxylate aminotransferase 2-like {ECO:0000250|UniProtKB:Q8TBG4};
GN   Name=eppl-1 {ECO:0000312|WormBase:T01B11.2a};
GN   ORFNames=T01B11.2 {ECO:0000312|WormBase:T01B11.2a};
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000250|UniProtKB:Q8TBG4};
CC   -!- SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000305}.
CC   -!- CAUTION: Does not seem to possess aminotransferase activity.
CC       {ECO:0000250|UniProtKB:Q8TBG4}.
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DR   EMBL; BX284604; CCD65920.1; -; Genomic_DNA.
DR   PIR; T25848; T25848.
DR   RefSeq; NP_001023346.1; NM_001028175.4.
DR   AlphaFoldDB; P91408; -.
DR   SMR; P91408; -.
DR   BioGRID; 42758; 2.
DR   DIP; DIP-24370N; -.
DR   STRING; 6239.T01B11.2a.1; -.
DR   EPD; P91408; -.
DR   PaxDb; P91408; -.
DR   PeptideAtlas; P91408; -.
DR   EnsemblMetazoa; T01B11.2a.1; T01B11.2a.1; WBGene00020139.
DR   GeneID; 177646; -.
DR   KEGG; cel:CELE_T01B11.2; -.
DR   UCSC; T01B11.2a.1; c. elegans.
DR   CTD; 177646; -.
DR   WormBase; T01B11.2a; CE12894; WBGene00020139; eppl-1.
DR   eggNOG; KOG1403; Eukaryota.
DR   GeneTree; ENSGT00940000171040; -.
DR   HOGENOM; CLU_016922_8_0_1; -.
DR   InParanoid; P91408; -.
DR   OMA; MVPNYNP; -.
DR   OrthoDB; 145181at2759; -.
DR   PhylomeDB; P91408; -.
DR   Reactome; R-CEL-1442490; Collagen degradation.
DR   Reactome; R-CEL-1483213; Synthesis of PE.
DR   Reactome; R-CEL-71064; Lysine catabolism.
DR   PRO; PR:P91408; -.
DR   Proteomes; UP000001940; Chromosome IV.
DR   Bgee; WBGene00020139; Expressed in larva and 4 other tissues.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; IEA:InterPro.
DR   CDD; cd00610; OAT_like; 1.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 1.
DR   InterPro; IPR005814; Aminotrans_3.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   Pfam; PF00202; Aminotran_3; 1.
DR   PIRSF; PIRSF000521; Transaminase_4ab_Lys_Orn; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1.
PE   3: Inferred from homology;
KW   Lyase; Pyridoxal phosphate; Reference proteome.
FT   CHAIN           1..467
FT                   /note="Ethanolamine-phosphate phospho-lyase homolog 1"
FT                   /id="PRO_0000120541"
FT   MOD_RES         307
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   467 AA;  51645 MW;  E5425970A6F73361 CRC64;
     MSTLVNALGF FTSSTPAAAA TKDVRSKEEI LKRRKDTIGS KCQIFYSDDP FMVSRASMQY
     LYDEKSNKFL DCISNVQHVG HCHPKVVEAI SKQLATSTCN VRFVSTQLTD CAEQILSTLP
     GLDTVLFCNS GSEANDLALR LARDYTKHKD AIVIEHAYHG HVTTTMELSP YKFDHGSTVS
     QPDWVHVAPC PDVFRGKHRL ADNELTNEDK LYAAGKQYSD DVKSILNDVE SRQCGVAAYF
     AEALQSCGGQ VIPPKDYFKD VATHVRNHGG LMIIDEVQTG FGRIGRKYWA HQLYDDGFLP
     DIVTMGKPMG NGFPVSAVAT RKEIADALGG EVGYFNTYGG NPVACAAVIS VMKVVKDENL
     LEHSQQMGEK LEVALRDLQK KHECIGDIRG VGLFWGIDLV KDRNTREPDQ KLAIATILAL
     RKSYGILLNA DGPHTNILKI KPPLCFNENN ILETVTALDQ VLTLMNR