EUTM_ECOL6
ID EUTM_ECOL6 Reviewed; 97 AA.
AC P0ABF5; P77606;
DT 25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=Bacterial microcompartment shell protein EutM;
DE AltName: Full=Bacterial microcompartment protein homohexamer {ECO:0000305};
DE Short=BMC-H {ECO:0000305};
DE AltName: Full=Ethanolamine utilization protein EutM;
GN Name=eutM; Synonyms=cchA; OrderedLocusNames=c2982;
OS Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=199310;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFT073 / ATCC 700928 / UPEC;
RX PubMed=12471157; DOI=10.1073/pnas.252529799;
RA Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA Donnenberg M.S., Blattner F.R.;
RT "Extensive mosaic structure revealed by the complete genome sequence of
RT uropathogenic Escherichia coli.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC -!- FUNCTION: Probably a major component of the bacterial microcompartment
CC (BMC) shell dedicated to ethanolamine degradation. Each homohexamer has
CC a central pore with an opening of up to 8.6 Angstroms. A positively-
CC charged funnel leads to the pore from each side of the hexamer. The
CC pore probably allows metabolite passage into and out of the BMC.
CC {ECO:0000250|UniProtKB:P0ABF4}.
CC -!- PATHWAY: Amine and polyamine degradation; ethanolamine degradation.
CC -!- SUBUNIT: Homohexamer with a central pore of up to 8.6 Angstroms
CC diameter. The hexamers pack into a two-dimensional array (By
CC similarity). Interacts with EutQ (By similarity).
CC {ECO:0000250|UniProtKB:P0ABF4, ECO:0000250|UniProtKB:P41791}.
CC -!- SUBCELLULAR LOCATION: Bacterial microcompartment
CC {ECO:0000250|UniProtKB:P41791}.
CC -!- SIMILARITY: Belongs to the bacterial microcompartments protein family.
CC {ECO:0000255|PROSITE-ProRule:PRU01278}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAN81432.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AE014075; AAN81432.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_000387713.1; NC_004431.1.
DR AlphaFoldDB; P0ABF5; -.
DR SMR; P0ABF5; -.
DR STRING; 199310.c2982; -.
DR EnsemblBacteria; AAN81432; AAN81432; c2982.
DR GeneID; 67416845; -.
DR KEGG; ecc:c2982; -.
DR eggNOG; COG4577; Bacteria.
DR HOGENOM; CLU_064903_5_0_6; -.
DR OMA; QFREGVN; -.
DR UniPathway; UPA00560; -.
DR Proteomes; UP000001410; Chromosome.
DR GO; GO:0031469; C:bacterial microcompartment; IEA:UniProtKB-SubCell.
DR GO; GO:0046336; P:ethanolamine catabolic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.30.70.1710; -; 1.
DR InterPro; IPR020808; Bact_microcomp_CS.
DR InterPro; IPR000249; BMC_dom.
DR InterPro; IPR037233; CcmK-like_sf.
DR InterPro; IPR044872; CcmK/CsoS1_BMC.
DR Pfam; PF00936; BMC; 1.
DR SMART; SM00877; BMC; 1.
DR SUPFAM; SSF143414; SSF143414; 1.
DR PROSITE; PS01139; BMC_1; 1.
DR PROSITE; PS51930; BMC_2; 1.
PE 3: Inferred from homology;
KW Bacterial microcompartment.
FT CHAIN 1..97
FT /note="Bacterial microcompartment shell protein EutM"
FT /id="PRO_0000042667"
FT DOMAIN 3..87
FT /note="BMC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01278"
SQ SEQUENCE 97 AA; 9866 MW; 0A4170FD8ABB8CF8 CRC64;
MEALGMIETR GLVALIEASD AMVKAARVKL VGVKQIGGGL CTAMVRGDVA ACKAATDAGA
AAAQRIGELV SVHVIPRPHG DLEEVFPIGL KGDSSNL
