ID   EUTS_SALTI              Reviewed;         111 AA.
AC   Q8Z4T3;
DT   23-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Bacterial microcompartment shell protein EutS;
DE   AltName: Full=Ethanolamine utilization protein EutS;
GN   Name=eutS; OrderedLocusNames=STY2706, t0389;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: A component of the bacterial microcompartment (BMC) shell
CC       dedicated to ethanolamine degradation. Its unusual hexameric shape may
CC       help form the BMC shell (By similarity). Targets at least 2 proteins
CC       (EutC and EutE) to the interior of the BMC (By similarity). Proteins
CC       such as EutS containing circularly permuted BMC domains may play a key
CC       role in conferring heterogeneity and flexibility in this BMC
CC       (Probable). {ECO:0000250|UniProtKB:P63746,
CC       ECO:0000250|UniProtKB:Q9ZFV7, ECO:0000305}.
CC   -!- PATHWAY: Amine and polyamine degradation; ethanolamine degradation.
CC   -!- SUBUNIT: Homohexamer with a central pore; the hexamer is not symmetric,
CC       it is bent by about 40 degrees; bending depends on Gly-39 (By
CC       similarity). Interacts with the N-terminus of EutC and of EutE,
CC       targeting them to the interior of the BMC (By similarity).
CC       {ECO:0000250|UniProtKB:P63746, ECO:0000250|UniProtKB:Q9ZFV7}.
CC   -!- SUBCELLULAR LOCATION: Bacterial microcompartment
CC       {ECO:0000250|UniProtKB:Q9ZFV7}.
CC   -!- DOMAIN: One side of the hexamer is concave and lined by hydrophobic
CC       residues, the other side has a slightly protruding, 6-stranded beta-
CC       barrel. {ECO:0000250|UniProtKB:P63746}.
CC   -!- SIMILARITY: Belongs to the EutS/PduU family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01279}.
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DR   EMBL; AL513382; CAD07700.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO68107.1; -; Genomic_DNA.
DR   RefSeq; NP_457004.1; NC_003198.1.
DR   RefSeq; WP_001031444.1; NZ_PZMG01000025.1.
DR   AlphaFoldDB; Q8Z4T3; -.
DR   SMR; Q8Z4T3; -.
DR   STRING; 220341.16503686; -.
DR   EnsemblBacteria; AAO68107; AAO68107; t0389.
DR   KEGG; stt:t0389; -.
DR   KEGG; sty:STY2706; -.
DR   PATRIC; fig|220341.7.peg.2743; -.
DR   eggNOG; COG4810; Bacteria.
DR   HOGENOM; CLU_143326_0_0_6; -.
DR   OMA; AMIAIND; -.
DR   UniPathway; UPA00560; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0031469; C:bacterial microcompartment; IEA:UniProtKB-SubCell.
DR   GO; GO:0046336; P:ethanolamine catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd07046; BMC_PduU-EutS; 1.
DR   Gene3D; 3.30.70.1710; -; 1.
DR   InterPro; IPR044870; BMC_CP.
DR   InterPro; IPR000249; BMC_dom.
DR   InterPro; IPR037233; CcmK-like_sf.
DR   InterPro; IPR009307; EutS/PduU/CutR.
DR   PANTHER; PTHR40449; PTHR40449; 1.
DR   Pfam; PF00936; BMC; 1.
DR   PIRSF; PIRSF012296; EutS_PduU; 1.
DR   SMART; SM00877; BMC; 1.
DR   SUPFAM; SSF143414; SSF143414; 1.
DR   PROSITE; PS51931; BMC_CP; 1.
PE   3: Inferred from homology;
KW   Bacterial microcompartment.
FT   CHAIN           1..111
FT                   /note="Bacterial microcompartment shell protein EutS"
FT                   /id="PRO_0000201522"
FT   DOMAIN          5..103
FT                   /note="BMC circularly permuted"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01279"
FT   CONFLICT        42
FT                   /note="D -> G (in Ref. 2; AAO68107)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   111 AA;  11731 MW;  DBA18196A574189E CRC64;
     MNKERIIQEF VPGKQVTLAH LIAHPGEELA KKIGVPDAGA IDIMTLTPGE TAMIAGDLAM
     KAADVHIGFL DRFSGALVIY GTVGAVEEAL LQTVSGLGRL LNFTLCELTK S