ID   EV45_EHV1B              Reviewed;         219 AA.
AC   P28981; Q6DLJ6;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   23-FEB-2022, entry version 68.
DE   RecName: Full=Envelope protein UL45 homolog;
GN   OrderedLocusNames=15;
OS   Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX   NCBI_TaxID=31520;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=1318606; DOI=10.1016/0042-6822(92)90706-u;
RA   Telford E.A.R., Watson M.S., McBride K., Davison A.J.;
RT   "The DNA sequence of equine herpesvirus-1.";
RL   Virology 189:304-316(1992).
RN   [2]
RP   FUNCTION, TOPOLOGY, AND GLYCOSYLATION.
RC   STRAIN=RacH, and RacL22;
RX   PubMed=11145911; DOI=10.1006/viro.2000.0690;
RA   Oettler D., Kaaden O.R., Neubauer A.;
RT   "The equine herpesvirus 1 UL45 homolog encodes a glycosylated type II
RT   transmembrane protein and is involved in virus egress.";
RL   Virology 279:302-312(2001).
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000250}; Single-pass type
CC       II membrane protein {ECO:0000250}.
CC   -!- PTM: N-glycosylated. {ECO:0000269|PubMed:11145911}.
CC   -!- SIMILARITY: Belongs to the herpesviridae HHV-1 UL45 family.
CC       {ECO:0000305}.
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DR   EMBL; AY665713; AAT67272.1; -; Genomic_DNA.
DR   SMR; P28981; -.
DR   Proteomes; UP000001189; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Glycoprotein; Membrane; Reference proteome; Signal-anchor; Transmembrane;
KW   Transmembrane helix; Viral envelope protein; Virion.
FT   CHAIN           1..219
FT                   /note="Envelope protein UL45 homolog"
FT                   /id="PRO_0000116165"
FT   TOPO_DOM        1..57
FT                   /note="Intravirion"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..78
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        79..219
FT                   /note="Virion surface"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        113
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        120
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        138
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   219 AA;  23800 MW;  7A7BF532ED2D775F CRC64;
     MEDYKLLQLE TATVDAQAPP LPTKTVPVFA PPLSTPPQPN ELVYTKRRRT KRKAKCRCLF
     FTMGMFALGV LMTTAILVST FILTVPIGAL RTAPCPAETF GLGDECVRPV LLNASSNTRN
     ISGVGAVCEE YSEMAASNGT AGLIMSLLDC LNVGDSESVM NKLNLDDTQL AYCNVPSFAE
     CYTKGFGVCY AARPLSPLGE LIYKARQALR LDHIIPFPR