ID   EX3L1_BOVIN             Reviewed;         739 AA.
AC   Q0VCR8;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Exocyst complex component 3-like protein;
GN   Name=EXOC3L1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: As part of the exocyst, may play a role in regulated
CC       exocytosis of insulin granules. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with EXOC2, EXOC4 and EXOC5; may be part of the
CC       exocyst. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle
CC       {ECO:0000250}. Note=Colocalizes with insulin granules. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SEC6 family. {ECO:0000305}.
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DR   EMBL; BC120037; AAI20038.1; -; mRNA.
DR   RefSeq; NP_001069350.1; NM_001075882.2.
DR   AlphaFoldDB; Q0VCR8; -.
DR   SMR; Q0VCR8; -.
DR   STRING; 9913.ENSBTAP00000015965; -.
DR   PaxDb; Q0VCR8; -.
DR   PRIDE; Q0VCR8; -.
DR   GeneID; 526306; -.
DR   KEGG; bta:526306; -.
DR   CTD; 283849; -.
DR   eggNOG; KOG2286; Eukaryota.
DR   InParanoid; Q0VCR8; -.
DR   OrthoDB; 391172at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0000145; C:exocyst; ISS:UniProtKB.
DR   GO; GO:0030141; C:secretory granule; ISS:UniProtKB.
DR   GO; GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
DR   GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR   GO; GO:0051601; P:exocyst localization; IBA:GO_Central.
DR   GO; GO:0006887; P:exocytosis; ISS:UniProtKB.
DR   GO; GO:0030072; P:peptide hormone secretion; ISS:UniProtKB.
DR   Gene3D; 1.10.357.70; -; 1.
DR   InterPro; IPR010326; EXOC3/Sec6.
DR   InterPro; IPR042532; EXOC3/Sec6_C.
DR   PANTHER; PTHR21292; PTHR21292; 1.
DR   Pfam; PF06046; Sec6; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasmic vesicle; Exocytosis; Reference proteome.
FT   CHAIN           1..739
FT                   /note="Exocyst complex component 3-like protein"
FT                   /id="PRO_0000309473"
FT   REGION          1..370
FT                   /note="Mediates interaction with EXOC2, EXOC4 and EXOC5"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   739 AA;  81295 MW;  D1A00A30C1BD3762 CRC64;
     MDSAARDKTQ PALPTGLEWP EQERAEQLAR GAALKWASGI FYRPEQLARL GQYRNREVQR
     TCSLEARIKS VVQSYLEGVK TGVWQLAQAL EAVQGAREAL GQARGLLRDM AEAAQTLEPL
     REQVVEHKQL QALSQLLPRL RAVPAAVAHT QTLIDAQRLL EAYVSLRELE QLQEETCVPL
     GGLELPVFEG LGPLAEALGQ AVEAAAGAAG QLARENPALL VAAVRVAEVD AGCTTSLEQA
     PRDWRQRCLR ALQQGLERVH FGTSLQPGPG ELAKWLEALR VALPAELAMA EALVAPCCPP
     HYKVVQLWAH TLHGGLRRCL QQLLEGPELE EADTFTLLHW VLHVYQGPEM MGSLELGPEA
     DVSDLEPLLT LENIEQLEAT FVAKVQAKVA QWLQKALDGE VVEWGREQEP DTDLSGFYHS
     PLPAIVLQIL EENIRVTRIV SVSLEQRVHG MALSELSAFL RSFTDALIRF SRDHLRGEAV
     VPHYVPYLLA TLNHQLALSS SVSVLQPKWV VPGVLAPVEA ELDKLQKRIC RLVLEALLAE
     LQPLFAALPS RRWLSSPELL DDVCKRTARF CQNFQHVRNP AVQLLLVEAE RTVVLQYLSA
     LMQGRLVCRG ADERTQAAER MQHDAAQLQE LFLGLGLEES VQCVPVLLAL KELLNLRDPT
     LLGLVVAGLR QQFPDVSEDH VSALLDLRGD VSREQRLAAL SSLRAGPQPS PQAGRRALFS
     LVPTPAPSLA SCFPSGSCA