ID   EX3L1_DANRE             Reviewed;         780 AA.
AC   A2AV37; A5D6T1;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Exocyst complex component 3-like protein;
GN   Name=exoc3l1; ORFNames=si:ch211-51l3.1;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: As part of the exocyst, may play a role in regulated
CC       exocytosis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SEC6 family. {ECO:0000305}.
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DR   EMBL; AL929309; CAM14260.1; -; Genomic_DNA.
DR   EMBL; BC139871; AAI39872.1; -; mRNA.
DR   RefSeq; NP_001092892.1; NM_001099422.1.
DR   AlphaFoldDB; A2AV37; -.
DR   SMR; A2AV37; -.
DR   STRING; 7955.ENSDARP00000094733; -.
DR   PaxDb; A2AV37; -.
DR   Ensembl; ENSDART00000103957; ENSDARP00000094733; ENSDARG00000051899.
DR   Ensembl; ENSDART00000193367; ENSDARP00000145185; ENSDARG00000114148.
DR   GeneID; 567832; -.
DR   KEGG; dre:567832; -.
DR   CTD; 283849; -.
DR   ZFIN; ZDB-GENE-061207-36; exoc3l1.
DR   eggNOG; KOG2286; Eukaryota.
DR   GeneTree; ENSGT01030000234613; -.
DR   HOGENOM; CLU_016260_1_0_1; -.
DR   InParanoid; A2AV37; -.
DR   OMA; EQEPNTD; -.
DR   OrthoDB; 391172at2759; -.
DR   PhylomeDB; A2AV37; -.
DR   TreeFam; TF314979; -.
DR   PRO; PR:A2AV37; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 25.
DR   Bgee; ENSDARG00000051899; Expressed in mature ovarian follicle and 19 other tissues.
DR   GO; GO:0000145; C:exocyst; IBA:GO_Central.
DR   GO; GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
DR   GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR   GO; GO:0051601; P:exocyst localization; IBA:GO_Central.
DR   GO; GO:0006887; P:exocytosis; IBA:GO_Central.
DR   Gene3D; 1.10.357.70; -; 1.
DR   InterPro; IPR010326; EXOC3/Sec6.
DR   InterPro; IPR042532; EXOC3/Sec6_C.
DR   PANTHER; PTHR21292; PTHR21292; 1.
DR   Pfam; PF06046; Sec6; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasmic vesicle; Exocytosis; Reference proteome.
FT   CHAIN           1..780
FT                   /note="Exocyst complex component 3-like protein"
FT                   /id="PRO_0000309476"
FT   CONFLICT        262
FT                   /note="T -> A (in Ref. 2; AAI39872)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        699
FT                   /note="K -> N (in Ref. 2; AAI39872)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   780 AA;  89082 MW;  878F16ED2784944B CRC64;
     MSDGDKNGRD NHEEALVPVE VWQELERAEC LARGAALKWA SGVFCRPEHL EKLGQYKKRE
     SQRTASIQSR LKSVVQSYLE GVDWGLGQLR EARAELRGVS HDLYKANLES RKNSEEVTTL
     ETLREISVSH CQLLAAVSNL PRLYKVRSMV LETERLVESR RLLEAHARLM ELERWQDEVL
     LQLQGPRGSS GTELNSEDEE LVRNYFSGVG RLVDALAKEL WAVVGSGLSL AHQNPTPFVS
     AVRIVEREEA LDQFFLEERR STSGHNIPMP AGRPRNWRDR FFKVMEEAVS ARFRSVSYLH
     TRGPGLASHL SALQHCIMGD LSTVRHCLEQ CVPAHYHLTR AYLHFCHQFL QTHLGLVSGW
     ELEGGEIFAV LNWVLHIYNS SEMMGEPALL AELEIENLGP LISQEGLEQL QNKYVQKVRK
     SVSEWMQKAL EVELTDWQRD QEPDIDHEGY YHTSLPTIIT QMLEENARVA LMISEALRDQ
     TIQMGLYEME KLLSRFRDAV IEFGKEHRKD PTVNKFYLHY LLACINNCII LKTSTESLQQ
     QICSFVSNRY SRIPLGPLAA LDRAVRKACR LVMDHLLFEL QPHLQELLSS TWLDQGDVTL
     NMCGVLERHC ELYNRVRQPC RQRLKEECQW LTVVEYVRAV MQKRLVCRSS DEQKQLAQRM
     TQDAQQLRDH LQSMEIDGTI GEVNPTALIA ALADIINLKD PGMLLLEISG LLSKYPDISE
     EHVSVLLDIR GDVPKEVRKS VLDFLDQSAP PLPPGYRPIF TEILVPSSSI PFCLPTAKCT