ID   AGUA_MYCCT              Reviewed;         364 AA.
AC   Q2SRJ6;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Putative agmatine deiminase {ECO:0000255|HAMAP-Rule:MF_01841};
DE            EC=3.5.3.12 {ECO:0000255|HAMAP-Rule:MF_01841};
DE   AltName: Full=Agmatine iminohydrolase {ECO:0000255|HAMAP-Rule:MF_01841};
GN   Name=aguA {ECO:0000255|HAMAP-Rule:MF_01841}; OrderedLocusNames=MCAP_0652;
OS   Mycoplasma capricolum subsp. capricolum (strain California kid / ATCC 27343
OS   / NCTC 10154).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=340047;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=California kid / ATCC 27343 / NCTC 10154;
RA   Glass J.I., Lartigue C., Pfannkoch C., Baden-Tillson H., Smith H.O.,
RA   Venter J.C., Roske K., Wise K.S., Calcutt M.J., Nelson W.C., Nierman W.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=agmatine + H2O = N-carbamoylputrescine + NH4(+);
CC         Xref=Rhea:RHEA:18037, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:58145, ChEBI:CHEBI:58318; EC=3.5.3.12;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01841};
CC   -!- SIMILARITY: Belongs to the agmatine deiminase family.
CC       {ECO:0000255|HAMAP-Rule:MF_01841}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000123; ABC01526.1; -; Genomic_DNA.
DR   RefSeq; WP_011387513.1; NC_007633.1.
DR   AlphaFoldDB; Q2SRJ6; -.
DR   SMR; Q2SRJ6; -.
DR   EnsemblBacteria; ABC01526; ABC01526; MCAP_0652.
DR   GeneID; 23778393; -.
DR   KEGG; mcp:MCAP_0652; -.
DR   HOGENOM; CLU_037682_1_0_14; -.
DR   OMA; WCRDHGP; -.
DR   OrthoDB; 771174at2; -.
DR   PhylomeDB; Q2SRJ6; -.
DR   Proteomes; UP000001928; Chromosome.
DR   GO; GO:0047632; F:agmatine deiminase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0004668; F:protein-arginine deiminase activity; IEA:InterPro.
DR   GO; GO:0009446; P:putrescine biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_01841; Agmatine_deimin; 1.
DR   InterPro; IPR017754; Agmatine_deiminase.
DR   InterPro; IPR007466; Peptidyl-Arg-deiminase_porph.
DR   PANTHER; PTHR31377; PTHR31377; 1.
DR   Pfam; PF04371; PAD_porph; 1.
DR   TIGRFAMs; TIGR03380; agmatine_aguA; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..364
FT                   /note="Putative agmatine deiminase"
FT                   /id="PRO_1000070558"
FT   ACT_SITE        355
FT                   /note="Amidino-cysteine intermediate"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01841"
SQ   SEQUENCE   364 AA;  41566 MW;  2B14ACC70D59B033 CRC64;
     MSKKMNSTPK KDGFWMPGEW EKHDQCWMIW PERSDNWRLG AKPAQRVFAN VANAIAKYEK
     VTMLVSHQQF ENARNLLDQN VRVIECSNDD SWMRDVGPTI VKNKDGEIRG VDWVFNAWGG
     FKGGLYFPWD KDDAIARKVC EISNIDYYRT DFVLEGGSIH TDGDGTLYTT EECLLNENRN
     PDLSKEQIEE NLKEYCGVEK VIWLPLGVYN DETNGHVDNL LHVVSPGHVV LTWTDDTTDP
     QYERSKLAYD ILTNTLDAKG RKIKVTKLHQ PGPLFITKEE AEGIDVCDTM SREPEQRMPA
     SYANFYIANN AIILPIFGDK YDDLAVKTLQ SVYPNHKIET VMAREILLGG GNIHCITQQQ
     PTTK