EX7S_GLAP5
ID EX7S_GLAP5 Reviewed; 74 AA.
AC B8F4R9;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 03-MAR-2009, sequence version 1.
DT 25-MAY-2022, entry version 67.
DE RecName: Full=Exodeoxyribonuclease 7 small subunit {ECO:0000255|HAMAP-Rule:MF_00337};
DE EC=3.1.11.6 {ECO:0000255|HAMAP-Rule:MF_00337};
DE AltName: Full=Exodeoxyribonuclease VII small subunit {ECO:0000255|HAMAP-Rule:MF_00337};
DE Short=Exonuclease VII small subunit {ECO:0000255|HAMAP-Rule:MF_00337};
GN Name=xseB {ECO:0000255|HAMAP-Rule:MF_00337}; OrderedLocusNames=HAPS_0673;
OS Glaesserella parasuis serovar 5 (strain SH0165) (Haemophilus parasuis).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Glaesserella.
OX NCBI_TaxID=557723;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SH0165;
RX PubMed=19074396; DOI=10.1128/jb.01682-08;
RA Yue M., Yang F., Yang J., Bei W., Cai X., Chen L., Dong J., Zhou R.,
RA Jin M., Jin Q., Chen H.;
RT "Complete genome sequence of Haemophilus parasuis SH0165.";
RL J. Bacteriol. 191:1359-1360(2009).
CC -!- FUNCTION: Bidirectionally degrades single-stranded DNA into large acid-
CC insoluble oligonucleotides, which are then degraded further into small
CC acid-soluble oligonucleotides. {ECO:0000255|HAMAP-Rule:MF_00337}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-
CC direction to yield nucleoside 5'-phosphates.; EC=3.1.11.6;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00337};
CC -!- SUBUNIT: Heterooligomer composed of large and small subunits.
CC {ECO:0000255|HAMAP-Rule:MF_00337}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00337}.
CC -!- SIMILARITY: Belongs to the XseB family. {ECO:0000255|HAMAP-
CC Rule:MF_00337}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001321; ACL32321.1; -; Genomic_DNA.
DR RefSeq; WP_005712345.1; NC_011852.1.
DR AlphaFoldDB; B8F4R9; -.
DR SMR; B8F4R9; -.
DR STRING; 557723.HAPS_0673; -.
DR EnsemblBacteria; ACL32321; ACL32321; HAPS_0673.
DR GeneID; 66619040; -.
DR KEGG; hap:HAPS_0673; -.
DR HOGENOM; CLU_145918_3_3_6; -.
DR OMA; PLNDYKG; -.
DR Proteomes; UP000006743; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
DR GO; GO:0008855; F:exodeoxyribonuclease VII activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006308; P:DNA catabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.287.1040; -; 1.
DR HAMAP; MF_00337; Exonuc_7_S; 1.
DR InterPro; IPR003761; Exonuc_VII_S.
DR InterPro; IPR037004; Exonuc_VII_ssu_sf.
DR PANTHER; PTHR34137; PTHR34137; 1.
DR Pfam; PF02609; Exonuc_VII_S; 1.
DR PIRSF; PIRSF006488; Exonuc_VII_S; 1.
DR SUPFAM; SSF116842; SSF116842; 1.
DR TIGRFAMs; TIGR01280; xseB; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Exonuclease; Hydrolase; Nuclease; Reference proteome.
FT CHAIN 1..74
FT /note="Exodeoxyribonuclease 7 small subunit"
FT /id="PRO_1000200254"
SQ SEQUENCE 74 AA; 8593 MW; B77A9E027A739C2F CRC64;
MAKKPTLDFE TTLKELEEIV NRLETGDLPL EEALNEFETA VKLVQQGQER LQKAEQRIQI
LLQKNEHADL TDYP
