AGUA_SHESM
ID AGUA_SHESM Reviewed; 370 AA.
AC Q0HF12;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2006, sequence version 1.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=Putative agmatine deiminase {ECO:0000255|HAMAP-Rule:MF_01841};
DE EC=3.5.3.12 {ECO:0000255|HAMAP-Rule:MF_01841};
DE AltName: Full=Agmatine iminohydrolase {ECO:0000255|HAMAP-Rule:MF_01841};
GN Name=aguA {ECO:0000255|HAMAP-Rule:MF_01841};
GN OrderedLocusNames=Shewmr4_3288;
OS Shewanella sp. (strain MR-4).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=60480;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR-4;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Nealson K.,
RA Konstantinidis K., Klappenbach J., Tiedje J., Richardson P.;
RT "Complete sequence of Shewanella sp. MR-4.";
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=agmatine + H2O = N-carbamoylputrescine + NH4(+);
CC Xref=Rhea:RHEA:18037, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938,
CC ChEBI:CHEBI:58145, ChEBI:CHEBI:58318; EC=3.5.3.12;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01841};
CC -!- SIMILARITY: Belongs to the agmatine deiminase family.
CC {ECO:0000255|HAMAP-Rule:MF_01841}.
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DR EMBL; CP000446; ABI40355.1; -; Genomic_DNA.
DR RefSeq; WP_011624023.1; NC_008321.1.
DR AlphaFoldDB; Q0HF12; -.
DR SMR; Q0HF12; -.
DR KEGG; she:Shewmr4_3288; -.
DR HOGENOM; CLU_037682_1_0_6; -.
DR OMA; WCRDHGP; -.
DR GO; GO:0047632; F:agmatine deiminase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0004668; F:protein-arginine deiminase activity; IEA:InterPro.
DR GO; GO:0009446; P:putrescine biosynthetic process; IEA:InterPro.
DR HAMAP; MF_01841; Agmatine_deimin; 1.
DR InterPro; IPR017754; Agmatine_deiminase.
DR InterPro; IPR007466; Peptidyl-Arg-deiminase_porph.
DR PANTHER; PTHR31377; PTHR31377; 1.
DR Pfam; PF04371; PAD_porph; 1.
DR TIGRFAMs; TIGR03380; agmatine_aguA; 1.
PE 3: Inferred from homology;
KW Hydrolase.
FT CHAIN 1..370
FT /note="Putative agmatine deiminase"
FT /id="PRO_1000070572"
FT ACT_SITE 361
FT /note="Amidino-cysteine intermediate"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01841"
SQ SEQUENCE 370 AA; 40706 MW; C09CA4B7CAAE5E37 CRC64;
MTNANVDATQ LTTKPSQDGF YMPAEWAAQQ AVWMIWPYRP DNWRSAGAYA QATFAKVADA
IGGATPVYMG VPQAFLAEAQ KVMPSHVTLV EIDSNDCWAR DTGPTVVVNA EGECRGVDWG
FNAWGGHNGG LYFPWDKDEQ VAAQMLKQHG FARYSAPLIL EGGSIHVDGE GTCMTTAECL
LNANRNPDLT KEQIEALLRD YLNVKQFIWL EEGVYMDETD GHIDNMCCFA RPGEVILHWT
DDETDPQYPR SKAALDVLQN TVDAQGRKLK IHLLPQPGPL YCTEEESKGV TEGTGVPRTA
GERLAGSYVN FLITNDRIVF PLLDPATDDI AAQKLQDIFP EHKIVGVPAR EILLGGGNIH
CITQQIPSGK