EXAS1_HUMAN
ID EXAS1_HUMAN Reviewed; 119 AA.
AC Q8N2X6; Q96CR9;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Uncharacterized protein EXOC3-AS1 {ECO:0000305};
DE AltName: Full=EXOC3 antisense RNA 1 {ECO:0000305};
DE AltName: Full=EXOC3 antisense gene protein 1 {ECO:0000305};
DE Flags: Precursor;
GN Name=EXOC3-AS1 {ECO:0000312|HGNC:HGNC:25175};
GN Synonyms=C5orf55 {ECO:0000312|HGNC:HGNC:25175};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15372022; DOI=10.1038/nature02919;
RA Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T.,
RA Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A.,
RA Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R.,
RA Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L.,
RA Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N.,
RA Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J.,
RA Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A.,
RA Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT "The DNA sequence and comparative analysis of human chromosome 5.";
RL Nature 431:268-274(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Colon;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q8N2X6; Q6A162: KRT40; NbExp=3; IntAct=EBI-749333, EBI-10171697;
CC Q8N2X6; Q8IUQ4: SIAH1; NbExp=3; IntAct=EBI-749333, EBI-747107;
CC Q8N2X6; Q12933: TRAF2; NbExp=4; IntAct=EBI-749333, EBI-355744;
CC Q8N2X6; P36406: TRIM23; NbExp=3; IntAct=EBI-749333, EBI-740098;
CC Q8N2X6; Q15654: TRIP6; NbExp=4; IntAct=EBI-749333, EBI-742327;
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH14011.2; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AC010442; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC014011; AAH14011.2; ALT_INIT; mRNA.
DR EMBL; BC029796; AAH29796.1; -; mRNA.
DR AlphaFoldDB; Q8N2X6; -.
DR SMR; Q8N2X6; -.
DR BioGRID; 125499; 7.
DR IntAct; Q8N2X6; 8.
DR MINT; Q8N2X6; -.
DR GlyGen; Q8N2X6; 1 site.
DR BioMuta; HGNC:25175; -.
DR PaxDb; Q8N2X6; -.
DR PRIDE; Q8N2X6; -.
DR GeneCards; EXOC3-AS1; -.
DR HGNC; HGNC:25175; EXOC3-AS1.
DR neXtProt; NX_Q8N2X6; -.
DR eggNOG; ENOG502TET6; Eukaryota.
DR InParanoid; Q8N2X6; -.
DR PathwayCommons; Q8N2X6; -.
DR SignaLink; Q8N2X6; -.
DR ChiTaRS; EXOC3-AS1; human.
DR Pharos; Q8N2X6; Tdark.
DR PRO; PR:Q8N2X6; -.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q8N2X6; protein.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE 1: Evidence at protein level;
KW Glycoprotein; Reference proteome; Secreted; Signal.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT CHAIN 19..119
FT /note="Uncharacterized protein EXOC3-AS1"
FT /id="PRO_0000348588"
FT REGION 23..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..78
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 44
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT VARIANT 50
FT /note="P -> S (in dbSNP:rs10035653)"
FT /id="VAR_046197"
FT VARIANT 118
FT /note="R -> G (in dbSNP:rs10035612)"
FT /id="VAR_046198"
SQ SEQUENCE 119 AA; 12661 MW; 0054C7CD3E6A8446 CRC64;
MPAVFMLASS SALQCGRGVP RFPRTEVGAG HSVNEETKAE KVGNQTSVIP ATSRQAALGT
SWTQRRTQPL QERSHWHPRG NNASGMGGHR MFPGPLRGPA AQVLENECGS LGRAAEGRS
