EXBB1_VIBCH
ID EXBB1_VIBCH Reviewed; 228 AA.
AC O52043; Q9KL37;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2000, sequence version 2.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Biopolymer transport protein exbB1;
GN Name=exbB1; Synonyms=exbB; OrderedLocusNames=VC_A0911;
OS Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=243277;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Classical CA401;
RX PubMed=9781885; DOI=10.1046/j.1365-2958.1998.01034.x;
RA Occhino D.A., Wyckoff E.E., Henderson D.P., Wrona T.J., Payne S.M.;
RT "Vibrio cholerae iron transport: haem transport genes are linked to one of
RT two sets of tonB, exbB, exbD genes.";
RL Mol. Microbiol. 29:1493-1507(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX PubMed=10952301; DOI=10.1038/35020000;
RA Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT cholerae.";
RL Nature 406:477-483(2000).
CC -!- FUNCTION: Involved in the TonB-dependent energy-dependent transport of
CC various receptor-bound substrates. Protects ExbD from proteolytic
CC degradation and functionally stabilizes TonB (By similarity).
CC {ECO:0000250}.
CC -!- SUBUNIT: The accessory proteins ExbB and ExbD seem to form a complex
CC with TonB. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the ExbB/TolQ family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF016580; AAB94545.1; -; Genomic_DNA.
DR EMBL; AE003853; AAF96808.1; -; Genomic_DNA.
DR PIR; C82400; C82400.
DR RefSeq; NP_233296.1; NC_002506.1.
DR RefSeq; WP_000445085.1; NZ_LT906615.1.
DR AlphaFoldDB; O52043; -.
DR SMR; O52043; -.
DR STRING; 243277.VC_A0911; -.
DR DNASU; 2612220; -.
DR EnsemblBacteria; AAF96808; AAF96808; VC_A0911.
DR KEGG; vch:VC_A0911; -.
DR PATRIC; fig|243277.26.peg.3526; -.
DR eggNOG; COG0811; Bacteria.
DR HOGENOM; CLU_053325_5_0_6; -.
DR OMA; GIWLQEK; -.
DR BioCyc; VCHO:VCA0911-MON; -.
DR Proteomes; UP000000584; Chromosome 2.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0017038; P:protein import; IBA:GO_Central.
DR InterPro; IPR002898; MotA_ExbB_proton_chnl.
DR Pfam; PF01618; MotA_ExbB; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..228
FT /note="Biopolymer transport protein exbB1"
FT /id="PRO_0000145813"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 116..136
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 9
FT /note="Q -> H (in Ref. 1; AAB94545)"
FT /evidence="ECO:0000305"
FT CONFLICT 183
FT /note="S -> N (in Ref. 1; AAB94545)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 228 AA; 24684 MW; 0CE2E0F27C3AE5A2 CRC64;
MESLQQLQQQ LGLMAWPLFI CSALTVMLLA ERLFQVLLSL TVGKGAIRHA LQATSPKNPK
QLAELTEHFA SKRPVLYRGV AMLLAHHQFD KSLREDAAGI WLQEQRHQFN SGLRLLTLIG
VISPLLGLLG TVLGLIEMFK GVAATTGSIT PNVLADGLGV AMYTTAAGLL IAVPAVAGAQ
LLSLWADRTM AKLEHTLNYV NLWLEGMTLH ADASLTVVTP QEATTENL
