EXBB_ECO57
ID EXBB_ECO57 Reviewed; 244 AA.
AC P0ABU8; P18783;
DT 25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Biopolymer transport protein ExbB;
GN Name=exbB; OrderedLocusNames=Z4359, ECs3890;
OS Escherichia coli O157:H7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- FUNCTION: Involved in the TonB-dependent energy-dependent transport of
CC various receptor-bound substrates. Protects ExbD from proteolytic
CC degradation and functionally stabilizes TonB (By similarity).
CC {ECO:0000250}.
CC -!- SUBUNIT: The accessory proteins ExbB and ExbD seem to form a complex
CC with TonB. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ExbB/TolQ family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE005174; AAG58142.1; -; Genomic_DNA.
DR EMBL; BA000007; BAB37313.1; -; Genomic_DNA.
DR PIR; B85960; B85960.
DR PIR; B91115; B91115.
DR RefSeq; NP_311917.1; NC_002695.1.
DR RefSeq; WP_000527844.1; NZ_SWKA01000005.1.
DR AlphaFoldDB; P0ABU8; -.
DR SMR; P0ABU8; -.
DR STRING; 155864.EDL933_4228; -.
DR PRIDE; P0ABU8; -.
DR EnsemblBacteria; AAG58142; AAG58142; Z4359.
DR EnsemblBacteria; BAB37313; BAB37313; ECs_3890.
DR GeneID; 67415048; -.
DR GeneID; 916284; -.
DR KEGG; ece:Z4359; -.
DR KEGG; ecs:ECs_3890; -.
DR PATRIC; fig|386585.9.peg.4058; -.
DR eggNOG; COG0811; Bacteria.
DR HOGENOM; CLU_053325_0_2_6; -.
DR OMA; PHMVKVG; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0043213; P:bacteriocin transport; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR002898; MotA_ExbB_proton_chnl.
DR InterPro; IPR014164; TonB_ExbB_1.
DR Pfam; PF01618; MotA_ExbB; 1.
DR TIGRFAMs; TIGR02797; exbB; 1.
PE 3: Inferred from homology;
KW Bacteriocin transport; Cell inner membrane; Cell membrane; Membrane;
KW Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..244
FT /note="Biopolymer transport protein ExbB"
FT /id="PRO_0000145800"
FT TOPO_DOM 1..15
FT /note="Periplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 16..39
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 40..127
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 128..155
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 156..161
FT /note="Periplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 162..194
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 195..244
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
SQ SEQUENCE 244 AA; 26287 MW; CEB63893A80BA71F CRC64;
MGNNLMQTDL SVWGMYQHAD IVVKCVMIGL ILASVVTWAI FFSKSVEFFN QKRRLKREQQ
LLAEARSLNQ ANDIAADFGS KSLSLHLLNE AQNELELSEG SDDNEGIKER TSFRLERRVA
AVGRQMGRGN GYLATIGAIS PFVGLFGTVW GIMNSFIGIA QTQTTNLAVV APGIAEALLA
TAIGLVAAIP AVVIYNVFAR QIGGFKAMLG DVAAQVLLLQ SRDLDLEASA AAHPVRVAQK
LRAG
