ID   EXBB_HAEIN              Reviewed;         150 AA.
AC   P43008;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Biopolymer transport protein ExbB;
GN   Name=exbB; OrderedLocusNames=HI_0253;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=NTHi TN106;
RX   PubMed=7828935; DOI=10.1016/0378-1119(94)00675-i;
RA   Jarosik G.P., Hansen E.J.;
RT   "Cloning and sequencing of the Haemophilus influenzae exbB and exbD
RT   genes.";
RL   Gene 152:89-92(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Involved in the TonB-dependent energy-dependent transport of
CC       various receptor-bound substrates. Protects ExbD from proteolytic
CC       degradation and functionally stabilizes TonB (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: The accessory proteins ExbB and ExbD seem to form a complex
CC       with TonB. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ExbB/TolQ family. {ECO:0000305}.
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DR   EMBL; U08209; AAA81948.1; -; Genomic_DNA.
DR   EMBL; L42023; AAC21919.1; -; Genomic_DNA.
DR   PIR; H64057; H64057.
DR   RefSeq; NP_438422.1; NC_000907.1.
DR   RefSeq; WP_005648856.1; NC_000907.1.
DR   AlphaFoldDB; P43008; -.
DR   SMR; P43008; -.
DR   STRING; 71421.HI_0253; -.
DR   EnsemblBacteria; AAC21919; AAC21919; HI_0253.
DR   KEGG; hin:HI_0253; -.
DR   PATRIC; fig|71421.8.peg.268; -.
DR   eggNOG; COG0811; Bacteria.
DR   HOGENOM; CLU_133317_0_0_6; -.
DR   OMA; WFVIERI; -.
DR   PhylomeDB; P43008; -.
DR   BioCyc; HINF71421:G1GJ1-267-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0017038; P:protein import; IBA:GO_Central.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR002898; MotA_ExbB_proton_chnl.
DR   InterPro; IPR014172; TonB_ExbB_2.
DR   Pfam; PF01618; MotA_ExbB; 1.
DR   TIGRFAMs; TIGR02805; exbB2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..150
FT                   /note="Biopolymer transport protein ExbB"
FT                   /id="PRO_0000145802"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        66..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        105..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   VARIANT         2
FT                   /note="V -> L (in strain: TN106)"
FT   VARIANT         25
FT                   /note="I -> V (in strain: TN106)"
FT   VARIANT         42
FT                   /note="S -> N (in strain: TN106)"
FT   VARIANT         58
FT                   /note="R -> S (in strain: TN106)"
FT   VARIANT         100
FT                   /note="V -> E (in strain: TN106)"
FT   VARIANT         144
FT                   /note="S -> N (in strain: TN106)"
SQ   SEQUENCE   150 AA;  16729 MW;  4FD9DD61C6CEC44A CRC64;
     MVQLFDFLQQ YSDYFIIGLL LLMSIIMLAM VIERYLFLRK VSVAHYSTIH ALDIDLNRNM
     TVISTIGANA PYVGLLGTVI GILLTFYQIG HGGGDIDPSV IMLHLSLALK ATALGILVAI
     PSMVFYNGLG RKVEVNRLKW KVLSEQKDKE