ID   EXBD_ECO57              Reviewed;         141 AA.
AC   P0ABV4; P18784;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Biopolymer transport protein ExbD;
GN   Name=exbD; OrderedLocusNames=Z4358, ECs3889;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Involved in the TonB-dependent energy-dependent transport of
CC       various receptor-bound substrates. {ECO:0000250}.
CC   -!- SUBUNIT: The accessory proteins ExbB and ExbD seem to form a complex
CC       with TonB. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Single-pass
CC       type II membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ExbD/TolR family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG58141.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB37312.1; -; Genomic_DNA.
DR   PIR; A85960; A85960.
DR   PIR; A98115; A98115.
DR   RefSeq; NP_311916.1; NC_002695.1.
DR   RefSeq; WP_001240712.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0ABV4; -.
DR   BMRB; P0ABV4; -.
DR   SMR; P0ABV4; -.
DR   STRING; 155864.EDL933_4227; -.
DR   EnsemblBacteria; AAG58141; AAG58141; Z4358.
DR   EnsemblBacteria; BAB37312; BAB37312; ECs_3889.
DR   GeneID; 67415049; -.
DR   GeneID; 916285; -.
DR   KEGG; ece:Z4358; -.
DR   KEGG; ecs:ECs_3889; -.
DR   PATRIC; fig|386585.9.peg.4057; -.
DR   eggNOG; COG0848; Bacteria.
DR   HOGENOM; CLU_085305_1_3_6; -.
DR   OMA; TQGKKDT; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0043213; P:bacteriocin transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR003400; ExbD.
DR   InterPro; IPR014170; TonB_ExbD_1.
DR   PANTHER; PTHR30558; PTHR30558; 1.
DR   Pfam; PF02472; ExbD; 1.
DR   TIGRFAMs; TIGR02803; ExbD_1; 1.
PE   3: Inferred from homology;
KW   Bacteriocin transport; Cell inner membrane; Cell membrane; Membrane;
KW   Protein transport; Reference proteome; Signal-anchor; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..141
FT                   /note="Biopolymer transport protein ExbD"
FT                   /id="PRO_0000129118"
FT   TOPO_DOM        1..22
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        23..43
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000305"
FT   TOPO_DOM        44..141
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   141 AA;  15527 MW;  25A539A2FAEB9F6C CRC64;
     MAMHLNENLD DNGEMHDINV TPFIDVMLVL LIIFMVAAPL ATVDVKVNLP ASTSTPQPRP
     EKPVYLSVKA DNSMFIGNDP VTDETMITAL NALTEGKKDT TIFFRADKTV DYETLMKVMD
     TLHQAGYLKI GLVGEETAKA K