ID   EXBD_HELPY              Reviewed;         129 AA.
AC   O25898;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Biopolymer transport protein ExbD;
GN   Name=exbD; OrderedLocusNames=HP_1340;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
CC   -!- FUNCTION: Involved in the TonB-dependent energy-dependent transport of
CC       various receptor-bound substrates. {ECO:0000250}.
CC   -!- SUBUNIT: The accessory proteins ExbB and ExbD seem to form a complex
CC       with TonB. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Single-pass
CC       type II membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ExbD/TolR family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE000511; AAD08382.1; -; Genomic_DNA.
DR   PIR; D64687; D64687.
DR   RefSeq; NP_208132.1; NC_000915.1.
DR   RefSeq; WP_000836350.1; NC_018939.1.
DR   AlphaFoldDB; O25898; -.
DR   SMR; O25898; -.
DR   DIP; DIP-3143N; -.
DR   IntAct; O25898; 1.
DR   MINT; O25898; -.
DR   STRING; 85962.C694_06915; -.
DR   PaxDb; O25898; -.
DR   EnsemblBacteria; AAD08382; AAD08382; HP_1340.
DR   KEGG; hpy:HP_1340; -.
DR   PATRIC; fig|85962.47.peg.1435; -.
DR   eggNOG; COG0848; Bacteria.
DR   OMA; VAIVTMK; -.
DR   PhylomeDB; O25898; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR003400; ExbD.
DR   InterPro; IPR014171; TonB_ExbD_2.
DR   PANTHER; PTHR30558; PTHR30558; 1.
DR   Pfam; PF02472; ExbD; 1.
DR   TIGRFAMs; TIGR02804; ExbD_2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..129
FT                   /note="Biopolymer transport protein ExbD"
FT                   /id="PRO_0000129122"
FT   TOPO_DOM        1..12
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        34..129
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   129 AA;  14377 MW;  D575395C4DDF28E9 CRC64;
     MKSIRRGDGL NVVPFIDIML VLLAIVLSIS TFIAQGKIKV SLPNAKNAEK SQPNDQKVVV
     ISVDEHDNIF VDDKPMNLEA LSAVVKQTDP KTLIDLKSDK SSRFETFISI MDILKEHNHE
     NFSISTQAQ