ID   EXBD_SHIFL              Reviewed;         141 AA.
AC   P0ABV5; P18784;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Biopolymer transport protein ExbD;
GN   Name=exbD; OrderedLocusNames=SF3050, S3253;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Involved in the TonB-dependent energy-dependent transport of
CC       various receptor-bound substrates. {ECO:0000250}.
CC   -!- SUBUNIT: The accessory proteins ExbB and ExbD seem to form a complex
CC       with TonB. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Single-pass
CC       type II membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ExbD/TolR family. {ECO:0000305}.
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DR   EMBL; AE005674; AAN44528.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP18340.1; -; Genomic_DNA.
DR   RefSeq; NP_708821.1; NC_004337.2.
DR   RefSeq; WP_001240712.1; NZ_WPGW01000034.1.
DR   AlphaFoldDB; P0ABV5; -.
DR   BMRB; P0ABV5; -.
DR   SMR; P0ABV5; -.
DR   STRING; 198214.SF3050; -.
DR   EnsemblBacteria; AAN44528; AAN44528; SF3050.
DR   EnsemblBacteria; AAP18340; AAP18340; S3253.
DR   GeneID; 1026651; -.
DR   GeneID; 67415049; -.
DR   KEGG; sfl:SF3050; -.
DR   KEGG; sfx:S3253; -.
DR   PATRIC; fig|198214.7.peg.3624; -.
DR   HOGENOM; CLU_085305_1_3_6; -.
DR   OMA; TQGKKDT; -.
DR   OrthoDB; 1940365at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0043213; P:bacteriocin transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR003400; ExbD.
DR   InterPro; IPR014170; TonB_ExbD_1.
DR   PANTHER; PTHR30558; PTHR30558; 1.
DR   Pfam; PF02472; ExbD; 1.
DR   TIGRFAMs; TIGR02803; ExbD_1; 1.
PE   3: Inferred from homology;
KW   Bacteriocin transport; Cell inner membrane; Cell membrane; Membrane;
KW   Protein transport; Reference proteome; Signal-anchor; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..141
FT                   /note="Biopolymer transport protein ExbD"
FT                   /id="PRO_0000129130"
FT   TOPO_DOM        1..22
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        23..43
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000305"
FT   TOPO_DOM        44..141
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   141 AA;  15527 MW;  25A539A2FAEB9F6C CRC64;
     MAMHLNENLD DNGEMHDINV TPFIDVMLVL LIIFMVAAPL ATVDVKVNLP ASTSTPQPRP
     EKPVYLSVKA DNSMFIGNDP VTDETMITAL NALTEGKKDT TIFFRADKTV DYETLMKVMD
     TLHQAGYLKI GLVGEETAKA K