EXC1L_HUMAN
ID EXC1L_HUMAN Reviewed; 172 AA.
AC A0A1B0GW35;
DT 31-JAN-2018, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2016, sequence version 1.
DT 03-AUG-2022, entry version 30.
DE RecName: Full=Exocyst complex component 1-like {ECO:0000305};
GN Name=EXOC1L {ECO:0000312|HGNC:HGNC:53433};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15815621; DOI=10.1038/nature03466;
RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA Wilson R.K.;
RT "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT 4.";
RL Nature 434:724-731(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 16-144.
RA Stevens M., Wei C., Gross S.S., McPherson J., Brent M.R.;
RT "Exhaustive RT-PCR and sequencing of all novel TWINSCAN predictions in
RT human.";
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AC110611; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471057; EAX05472.1; -; Genomic_DNA.
DR EMBL; DN831484; -; NOT_ANNOTATED_CDS; mRNA.
DR CCDS; CCDS87223.1; -.
DR AlphaFoldDB; A0A1B0GW35; -.
DR SMR; A0A1B0GW35; -.
DR BioMuta; EXOC1L; -.
DR PeptideAtlas; A0A1B0GW35; -.
DR Ensembl; ENST00000636125.2; ENSP00000490760.1; ENSG00000250821.3.
DR MANE-Select; ENST00000636125.2; ENSP00000490760.1; NM_001351574.3; NP_001338503.1.
DR GeneCards; EXOC1L; -.
DR HGNC; HGNC:53433; EXOC1L.
DR HPA; ENSG00000250821; Not detected.
DR neXtProt; NX_A0A1B0GW35; -.
DR OpenTargets; ENSG00000250821; -.
DR VEuPathDB; HostDB:ENSG00000250821; -.
DR GeneTree; ENSGT00940000162193; -.
DR OMA; EVEICMV; -.
DR Pharos; A0A1B0GW35; Tdark.
DR PRO; PR:A0A1B0GW35; -.
DR Proteomes; UP000005640; Chromosome 4.
DR RNAct; A0A1B0GW35; protein.
DR Bgee; ENSG00000250821; Expressed in caudate nucleus and 41 other tissues.
DR ExpressionAtlas; A0A1B0GW35; baseline and differential.
DR GO; GO:0000145; C:exocyst; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IBA:GO_Central.
DR GO; GO:0006887; P:exocytosis; IBA:GO_Central.
DR GO; GO:0006893; P:Golgi to plasma membrane transport; IBA:GO_Central.
DR InterPro; IPR028258; Sec3-PIP2_bind.
DR Pfam; PF15277; Sec3-PIP2_bind; 1.
DR SMART; SM01313; Sec3-PIP2_bind; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..172
FT /note="Exocyst complex component 1-like"
FT /id="PRO_0000442936"
SQ SEQUENCE 172 AA; 20250 MW; F405E2F1D98029D8 CRC64;
MSSLVKEDLE KKLFKPLSQN LYEFIEIEFS VQDRYYLCVS VTKKEEVKIV MVKHYRIGLD
EKYEVTKKWS LNDLQMIDGK EADTDNPFFD LHFKKVYSLE AYSCASKYAF ARTVNKLNHA
YLKKDLQIVN FDSTYINDDS IWSSNNKDCL VLMRICFYAF NLVCLSLCPL PL
