ID   EXC_ECOLX               Reviewed;         220 AA.
AC   P05839;
DT   01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1988, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Exclusion-determining protein;
GN   Name=exc;
OS   Escherichia coli.
OG   Plasmid IncI1 R144.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3721199; DOI=10.1016/0378-1119(86)90156-3;
RA   Hartskeerl R., Overduin P., Hoekstra W., Tommassen J.;
RT   "Nucleotide sequence of the exclusion-determining locus of IncI plasmid
RT   R144.";
RL   Gene 42:107-111(1986).
CC   -!- MISCELLANEOUS: Conjugative plasmids generally prevent the effective
CC       entry of donor DNA from other cells carrying identical (or closely
CC       related) plasmids by encoding a barrier in the cell envelope. In R144
CC       this type of exclusion affects only DNA transfer.
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DR   EMBL; M13492; AAA26077.1; -; Genomic_DNA.
DR   PIR; A24466; NXEC.
DR   RefSeq; WP_000644794.1; NZ_WVVK01000025.1.
DR   RefSeq; YP_006903452.1; NC_019044.1.
DR   RefSeq; YP_009069649.1; NC_025147.1.
DR   AlphaFoldDB; P05839; -.
DR   GeneID; 39514937; -.
DR   GeneID; 66562609; -.
DR   InterPro; IPR016389; Exclusion-determining_protein.
DR   PIRSF; PIRSF003281; ExcA; 1.
PE   4: Predicted;
KW   Plasmid.
FT   CHAIN           1..220
FT                   /note="Exclusion-determining protein"
FT                   /id="PRO_0000068348"
SQ   SEQUENCE   220 AA;  25756 MW;  F48BA7A3B4A9A364 CRC64;
     MKAKKETTDR FPTWWLFYYV LRKAYFFLGI PFFLFCALGF TEMLCSDRYF GNKVEDYVVT
     FGSWFLLLAP GIWMYSRAKT RREKIRKVVQ TIKESGFYSP EKGYEGLSLT QGAYFGIDLK
     NGTMLYVRIY PGNIMDVIGF DIHNFTRTVT DDKKLEIHTK YINLPMVPVP SWCAHPETAS
     NTMHAMASRG YDYPVDFPRL IQEKRKEWEQ IAGMPVAEVF