ID   EXG3_SCHPO              Reviewed;         464 AA.
AC   O74799;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 125.
DE   RecName: Full=Glucan 1,3-beta-glucosidase 3;
DE            EC=3.2.1.58;
DE   AltName: Full=Exo-1,3-beta-glucanase 3;
GN   Name=exg3; ORFNames=SPBC2D10.05;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Successive hydrolysis of beta-D-glucose units from the non-
CC         reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose.;
CC         EC=3.2.1.58;
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC       {ECO:0000305}.
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DR   EMBL; CU329671; CAA21163.1; -; Genomic_DNA.
DR   PIR; T40108; T40108.
DR   RefSeq; NP_596224.1; NM_001022144.2.
DR   AlphaFoldDB; O74799; -.
DR   SMR; O74799; -.
DR   BioGRID; 276827; 32.
DR   STRING; 4896.SPBC2D10.05.1; -.
DR   CAZy; GH5; Glycoside Hydrolase Family 5.
DR   MaxQB; O74799; -.
DR   PaxDb; O74799; -.
DR   EnsemblFungi; SPBC2D10.05.1; SPBC2D10.05.1:pep; SPBC2D10.05.
DR   GeneID; 2540296; -.
DR   KEGG; spo:SPBC2D10.05; -.
DR   PomBase; SPBC2D10.05; exg3.
DR   VEuPathDB; FungiDB:SPBC2D10.05; -.
DR   eggNOG; ENOG502QVVM; Eukaryota.
DR   HOGENOM; CLU_004624_8_2_1; -.
DR   InParanoid; O74799; -.
DR   OMA; WTYKKEH; -.
DR   PhylomeDB; O74799; -.
DR   PRO; PR:O74799; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:1990819; C:actin fusion focus; IDA:PomBase.
DR   GO; GO:0009986; C:cell surface; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IDA:PomBase.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005576; C:extracellular region; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0008422; F:beta-glucosidase activity; IBA:GO_Central.
DR   GO; GO:0046557; F:glucan endo-1,6-beta-glucosidase activity; IDA:PomBase.
DR   GO; GO:0004338; F:glucan exo-1,3-beta-glucosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006073; P:cellular glucan metabolic process; IBA:GO_Central.
DR   GO; GO:0070879; P:fungal-type cell wall beta-glucan metabolic process; IMP:PomBase.
DR   GO; GO:1904541; P:fungal-type cell wall disassembly involved in conjugation with cellular fusion; IGI:PomBase.
DR   GO; GO:0009251; P:glucan catabolic process; IBA:GO_Central.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   PROSITE; PS00659; GLYCOSYL_HYDROL_F5; 1.
PE   3: Inferred from homology;
KW   Cell wall biogenesis/degradation; Glycosidase; Hydrolase;
KW   Reference proteome.
FT   CHAIN           1..464
FT                   /note="Glucan 1,3-beta-glucosidase 3"
FT                   /id="PRO_0000184054"
SQ   SEQUENCE   464 AA;  53702 MW;  60758FAB269745B1 CRC64;
     MGLNKQDLYI YRKQYGVNLG AWFCAERWIN DFLFTGEGSS ELEAVSGNVK AHGIDKAREN
     FEAHWKSWIG IEDFSYMKQH LVNSVRIPLG YWSLGNDELV KGTPFEPYAE VYRNSLHILC
     EKIQEAGSLS IGVLLDFHGV YGGGNCDGHS GTSSGKAEFY EKQEYQDRTV EAVKFLSSKI
     GQFENVIGIQ VINEPIWGQY DVLANFYQKA RSVVPSYLPV YIGDGWDKDH WVNWVNDHES
     EGFYVVDHHS YFCFGGELCH APPKLITRRL DTGEEYGKTK LSNIVIGEWS CTLSQESWSQ
     TKLHDKRRRD FGEAQLNQYL NYCGGCFFWT YKFLHGKGGD WDFRSVVEDK VINYPPPPPT
     ENKAMPALLE QSRDQNFGGH CYYWDQKQHD HPYEHDLYVK GWNQAWEDYI EFLQHGAMIG
     FPRAWTQKRM TSISSASAWE YRDGMNAAWL HLERMGFLNP FRHP