EXLA3_ARATH
ID EXLA3_ARATH Reviewed; 263 AA.
AC Q9LZT5; Q1LYV3; Q8GZA5;
DT 05-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Expansin-like A3;
DE Short=At-EXPL3;
DE Short=AtEXLA3;
DE Short=AtEXPL3;
DE AltName: Full=Ath-ExpBeta-2.3;
DE Flags: Precursor;
GN Name=EXLA3; Synonyms=EXPL3; OrderedLocusNames=At3g45960;
GN ORFNames=F16L2_170;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NOMENCLATURE.
RX PubMed=15604683; DOI=10.1007/s11103-004-0158-6;
RA Kende H., Bradford K.J., Brummell D.A., Cho H.-T., Cosgrove D.J.,
RA Fleming A.J., Gehring C., Lee Y., McQueen-Mason S.J., Rose J.K.C.,
RA Voesenek L.A.C.;
RT "Nomenclature for members of the expansin superfamily of genes and
RT proteins.";
RL Plant Mol. Biol. 55:311-314(2004).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9LZT5-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9LZT5-2; Sequence=VSP_016536;
CC -!- MISCELLANEOUS: [Isoform 2]: May be due to an intron retention.
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the expansin family. Expansin-like A subfamily.
CC {ECO:0000305}.
CC -!- WEB RESOURCE: Name=EXPANSIN homepage;
CC URL="http://homes.bio.psu.edu/expansins/";
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DR EMBL; AL162459; CAB82820.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78094.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78095.1; -; Genomic_DNA.
DR EMBL; AK117110; BAC41789.1; -; mRNA.
DR EMBL; BT025273; ABF19026.1; -; mRNA.
DR PIR; T47536; T47536.
DR RefSeq; NP_001030815.1; NM_001035738.3. [Q9LZT5-1]
DR RefSeq; NP_190182.2; NM_114465.4. [Q9LZT5-2]
DR AlphaFoldDB; Q9LZT5; -.
DR SMR; Q9LZT5; -.
DR STRING; 3702.AT3G45960.2; -.
DR PaxDb; Q9LZT5; -.
DR PRIDE; Q9LZT5; -.
DR ProteomicsDB; 222235; -. [Q9LZT5-1]
DR EnsemblPlants; AT3G45960.1; AT3G45960.1; AT3G45960. [Q9LZT5-2]
DR EnsemblPlants; AT3G45960.2; AT3G45960.2; AT3G45960. [Q9LZT5-1]
DR GeneID; 823739; -.
DR Gramene; AT3G45960.1; AT3G45960.1; AT3G45960. [Q9LZT5-2]
DR Gramene; AT3G45960.2; AT3G45960.2; AT3G45960. [Q9LZT5-1]
DR KEGG; ath:AT3G45960; -.
DR Araport; AT3G45960; -.
DR TAIR; locus:2077167; AT3G45960.
DR eggNOG; ENOG502QSGZ; Eukaryota.
DR InParanoid; Q9LZT5; -.
DR OMA; CKDGELC; -.
DR PhylomeDB; Q9LZT5; -.
DR PRO; PR:Q9LZT5; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LZT5; baseline and differential.
DR Genevisible; Q9LZT5; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0009505; C:plant-type cell wall; HDA:TAIR.
DR GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR Gene3D; 2.40.40.10; -; 1.
DR Gene3D; 2.60.40.760; -; 1.
DR InterPro; IPR007118; Expan_Lol_pI.
DR InterPro; IPR007112; Expansin/allergen_DPBB_dom.
DR InterPro; IPR007117; Expansin_CBD.
DR InterPro; IPR036749; Expansin_CBD_sf.
DR InterPro; IPR009009; RlpA-like_DPBB.
DR InterPro; IPR036908; RlpA-like_sf.
DR Pfam; PF03330; DPBB_1; 1.
DR Pfam; PF01357; Expansin_C; 1.
DR PRINTS; PR01225; EXPANSNFAMLY.
DR SMART; SM00837; DPBB_1; 1.
DR SUPFAM; SSF49590; SSF49590; 1.
DR SUPFAM; SSF50685; SSF50685; 1.
DR PROSITE; PS50843; EXPANSIN_CBD; 1.
DR PROSITE; PS50842; EXPANSIN_EG45; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Glycoprotein; Reference proteome; Secreted; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..263
FT /note="Expansin-like A3"
FT /id="PRO_0000008714"
FT DOMAIN 41..147
FT /note="Expansin-like EG45"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
FT DOMAIN 161..243
FT /note="Expansin-like CBD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00078"
FT CARBOHYD 99
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 102
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT VAR_SEQ 1..48
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:11910074, ECO:0000303|Ref.4"
FT /id="VSP_016536"
SQ SEQUENCE 263 AA; 28559 MW; 5D8A2048FEA7C292 CRC64;
MRSFLYLIVV IFLFSSSVNA CDRCLHRSKA SYFSSASALS SGACAYGPMA TSFFAGHIAA
AIPSIYKDGA GCGACFQVRC KNPKLCNSKG TIVMVTDLNT SNQTDLVLSS RAFRAMAKPV
VGVDKYLLKQ GIVDVEYQRV PCNYGKRNLN VRVEEASKKP NYLAIKLLYQ GGQTEVVGID
IAPVGSSQWS YMSRSHGAVW ATDKVPTGAL QFKFTVTGGY DGKTVWSKRV LPANWNSGRI
YDAGVQITDI AQEGCDTCGH IWN
