ID   EXO70_ASPFU             Reviewed;         628 AA.
AC   Q4X0X6;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Exocyst complex protein exo70;
GN   Name=exo70; ORFNames=AFUA_2G11960;
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=330879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA   Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA   Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA   Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA   Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA   Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA   Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA   O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA   Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA   Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA   Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA   Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA   Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA   Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA   Barrell B.G., Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- FUNCTION: Involved in the secretory pathway as part of the exocyst
CC       complex which tethers secretory vesicles to the sites of exocytosis.
CC       Also plays a role in the assembly of the exocyst (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Bud {ECO:0000250}. Bud neck {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EXO70 family. {ECO:0000305}.
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DR   EMBL; AAHF01000001; EAL93489.1; -; Genomic_DNA.
DR   RefSeq; XP_755527.1; XM_750434.1.
DR   AlphaFoldDB; Q4X0X6; -.
DR   SMR; Q4X0X6; -.
DR   STRING; 746128.CADAFUBP00002706; -.
DR   PRIDE; Q4X0X6; -.
DR   EnsemblFungi; EAL93489; EAL93489; AFUA_2G11960.
DR   GeneID; 3513574; -.
DR   KEGG; afm:AFUA_2G11960; -.
DR   VEuPathDB; FungiDB:Afu2g11960; -.
DR   eggNOG; KOG2344; Eukaryota.
DR   HOGENOM; CLU_010236_4_2_1; -.
DR   InParanoid; Q4X0X6; -.
DR   OMA; GPIYGNT; -.
DR   OrthoDB; 410847at2759; -.
DR   Proteomes; UP000002530; Chromosome 2.
DR   GO; GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.
DR   GO; GO:0000145; C:exocyst; IBA:GO_Central.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:InterPro.
DR   GO; GO:0006887; P:exocytosis; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR004140; Exo70.
DR   InterPro; IPR046364; Exo70_C.
DR   PANTHER; PTHR12542; PTHR12542; 1.
DR   Pfam; PF03081; Exo70; 1.
DR   SUPFAM; SSF74788; SSF74788; 1.
PE   3: Inferred from homology;
KW   Exocytosis; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..628
FT                   /note="Exocyst complex protein exo70"
FT                   /id="PRO_0000118965"
SQ   SEQUENCE   628 AA;  68846 MW;  CD7C95CB4B62D6B7 CRC64;
     MVAPRHNAYA EESAEVEVLY ANLEKLKLLT KKIQGSLVRL ETGGNVVKHA IGPIYSNTQS
     LQITNSNIDK VNEAIERLRQ PLDAKNREEG IIRAGPQSVE LSQYLAAMKR VDKALVDLSS
     TNLKSNQKAI SEFNNLLSTG NAKLQDMLRG ILNQYASPIE PLHYLTKDLP FPSIPQETIS
     ELTSICAAID SAASHGPQRG DGGNPALKIY ADVRGAYLTS SLQNLAIASL NTVKRRAADG
     PYKQGTNGIG IYSNALENFI STEYEIIAQI FTGDQRGLAL QTTFRSALAE YSKTLRELNE
     YIKANLMTDC FLAFEIIEIV TAMSYRVDSR TGELKSLFIE ALRPVRETAK SSLSELLEET
     KRKAASIPVL PPDGGSVPLV NEVMSSLTTL TGYSGPLASI LTSLGDGNWR STANASGTAP
     LDVSPDSSAL LSHFILDMIE ALMSSLEARG RALHRSKAVQ GVFLSNVFCI VDRAIRQSPE
     LARHLGTPDS IARIDTFRKR ATSTYLDAWK ETSQYLLDVQ YTSRAGARPA SGGIVDSSAI
     VKSLSSKDKD AIKDKFKAFN ASFDELVNRH KALYMEREVR GVLAREVQAV LEPLYARFWD
     RYHEIDKGRG KYVKYDKGSL SAQLAALA