ID   EXO70_EMENI             Reviewed;         631 AA.
AC   Q5AZS0; C8V1U3;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Exocyst complex protein exo70;
GN   Name=exo70; ORFNames=AN6210;
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS   M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=227321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA   Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA   Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA   Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA   Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA   Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA   Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA   Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA   Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA   Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA   Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA   Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA   Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA   Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA   van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA   Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA   Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA   Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA   Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA   Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA   van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA   Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA   Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT   effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
CC   -!- FUNCTION: Involved in the secretory pathway as part of the exocyst
CC       complex which tethers secretory vesicles to the sites of exocytosis.
CC       Also plays a role in the assembly of the exocyst (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Bud {ECO:0000250}. Bud neck {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EXO70 family. {ECO:0000305}.
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DR   EMBL; AACD01000105; EAA57996.1; -; Genomic_DNA.
DR   EMBL; BN001301; CBF69955.1; -; Genomic_DNA.
DR   RefSeq; XP_663814.1; XM_658722.1.
DR   AlphaFoldDB; Q5AZS0; -.
DR   SMR; Q5AZS0; -.
DR   STRING; 162425.CADANIAP00006794; -.
DR   EnsemblFungi; CBF69955; CBF69955; ANIA_06210.
DR   EnsemblFungi; EAA57996; EAA57996; AN6210.2.
DR   GeneID; 2870804; -.
DR   KEGG; ani:AN6210.2; -.
DR   VEuPathDB; FungiDB:AN6210; -.
DR   eggNOG; KOG2344; Eukaryota.
DR   HOGENOM; CLU_010236_4_2_1; -.
DR   InParanoid; Q5AZS0; -.
DR   OMA; GPIYGNT; -.
DR   OrthoDB; 410847at2759; -.
DR   Proteomes; UP000000560; Chromosome I.
DR   Proteomes; UP000005890; Unassembled WGS sequence.
DR   GO; GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.
DR   GO; GO:0000145; C:exocyst; IBA:GO_Central.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:InterPro.
DR   GO; GO:0006887; P:exocytosis; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR004140; Exo70.
DR   InterPro; IPR046364; Exo70_C.
DR   PANTHER; PTHR12542; PTHR12542; 1.
DR   Pfam; PF03081; Exo70; 1.
DR   SUPFAM; SSF74788; SSF74788; 1.
PE   3: Inferred from homology;
KW   Exocytosis; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..631
FT                   /note="Exocyst complex protein exo70"
FT                   /id="PRO_0000118969"
SQ   SEQUENCE   631 AA;  70207 MW;  850C8ECAEA67EF07 CRC64;
     MVAPRDTAFA EESAEVEVLY ANLEKLKRLT KKIQGSLVRL ETGGNVVKHA IGPIYSNTQS
     LQITNNNIDR VIEAIERLRQ PLDAKNREEG VIRAGPQPNN LPQYLAAMRG VNDALMDLTS
     TNLKSNQKAI SEFTSLLGIG NSKLQDLLRL KLGEHVSPIE PLHYLTKDLP FPTIPEDRIA
     EIAPICAAIN SAAVHVPHRG EGGSPALKIY ADVRGPYIST SAQNLAIASL NTLKRRVDDE
     SPYKQGTNGI GTYSDALENF IYAEWEAIKR IFTGDHRGLA LQMTCRSAIA EYSKTIRELN
     DYIRTNLLTD CFLAFEIIDI VTAKSYDIEL KTGELKSLFL EALRPVRETA KYSLAELLEE
     TKRRAQAIPM LPPNGAPTPL VDKVMRSLIE LTGYQKPLAS ILTSLGDGNW RSTSASSMNT
     PLDVNPDSDV LFSHFILDVI ETLLIALEAR ARQLHRTKAA QGVFLSNVFC LVDRAIRSSP
     ELARFLGSPD SVSRIDTFRK RATSTYLDAW KETSHYLLDV QYTSHTRGGS RPQSGGAVDS
     SAIVKSLSSR DKDAIKDKFK AFNASFDDLV ARHKSFYMER EVRSVLAREV QAVLEPLYAR
     FYDRYHELDK GRGKYTKYDK GSLSAQLASL Q