ID   EXO70_GIBZE             Reviewed;         632 AA.
AC   Q4ILI9; A0A0E0RS99; V6R5X0;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2005, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Exocyst complex protein EXO70;
GN   Name=EXO70; ORFNames=FGRRES_01919, FGSG_01919;
OS   Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084
OS   / PH-1) (Wheat head blight fungus) (Fusarium graminearum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX   NCBI_TaxID=229533;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX   PubMed=17823352; DOI=10.1126/science.1143708;
RA   Cuomo C.A., Gueldener U., Xu J.-R., Trail F., Turgeon B.G., Di Pietro A.,
RA   Walton J.D., Ma L.-J., Baker S.E., Rep M., Adam G., Antoniw J., Baldwin T.,
RA   Calvo S.E., Chang Y.-L., DeCaprio D., Gale L.R., Gnerre S., Goswami R.S.,
RA   Hammond-Kosack K., Harris L.J., Hilburn K., Kennell J.C., Kroken S.,
RA   Magnuson J.K., Mannhaupt G., Mauceli E.W., Mewes H.-W., Mitterbauer R.,
RA   Muehlbauer G., Muensterkoetter M., Nelson D., O'Donnell K., Ouellet T.,
RA   Qi W., Quesneville H., Roncero M.I.G., Seong K.-Y., Tetko I.V., Urban M.,
RA   Waalwijk C., Ward T.J., Yao J., Birren B.W., Kistler H.C.;
RT   "The Fusarium graminearum genome reveals a link between localized
RT   polymorphism and pathogen specialization.";
RL   Science 317:1400-1402(2007).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX   PubMed=20237561; DOI=10.1038/nature08850;
RA   Ma L.-J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.-J.,
RA   Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA   Houterman P.M., Kang S., Shim W.-B., Woloshuk C., Xie X., Xu J.-R.,
RA   Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA   Butchko R.A.E., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.J.,
RA   Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA   Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA   Kumar L., Lee Y.-H., Li L., Manners J.M., Miranda-Saavedra D.,
RA   Mukherjee M., Park G., Park J., Park S.-Y., Proctor R.H., Regev A.,
RA   Ruiz-Roldan M.C., Sain D., Sakthikumar S., Sykes S., Schwartz D.C.,
RA   Turgeon B.G., Wapinski I., Yoder O., Young S., Zeng Q., Zhou S.,
RA   Galagan J., Cuomo C.A., Kistler H.C., Rep M.;
RT   "Comparative genomics reveals mobile pathogenicity chromosomes in
RT   Fusarium.";
RL   Nature 464:367-373(2010).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX   PubMed=26198851; DOI=10.1186/s12864-015-1756-1;
RA   King R., Urban M., Hammond-Kosack M.C.U., Hassani-Pak K.,
RA   Hammond-Kosack K.E.;
RT   "The completed genome sequence of the pathogenic ascomycete fungus Fusarium
RT   graminearum.";
RL   BMC Genomics 16:544-544(2015).
CC   -!- FUNCTION: Involved in the secretory pathway as part of the exocyst
CC       complex which tethers secretory vesicles to the sites of exocytosis.
CC       Also plays a role in the assembly of the exocyst (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Bud {ECO:0000250}. Bud neck {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EXO70 family. {ECO:0000305}.
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DR   EMBL; DS231663; ESU07285.1; -; Genomic_DNA.
DR   EMBL; HG970332; CEF74124.1; -; Genomic_DNA.
DR   RefSeq; XP_011317770.1; XM_011319468.1.
DR   AlphaFoldDB; Q4ILI9; -.
DR   SMR; Q4ILI9; -.
DR   STRING; 5518.FGSG_01919P0; -.
DR   EnsemblFungi; ESU07285; ESU07285; FGSG_01919.
DR   GeneID; 23549330; -.
DR   KEGG; fgr:FGSG_01919; -.
DR   VEuPathDB; FungiDB:FGRAMPH1_01G04635; -.
DR   eggNOG; KOG2344; Eukaryota.
DR   HOGENOM; CLU_010236_4_2_1; -.
DR   InParanoid; Q4ILI9; -.
DR   Proteomes; UP000070720; Chromosome 1.
DR   GO; GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.
DR   GO; GO:0000145; C:exocyst; IEA:InterPro.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:InterPro.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR004140; Exo70.
DR   InterPro; IPR046364; Exo70_C.
DR   PANTHER; PTHR12542; PTHR12542; 1.
DR   Pfam; PF03081; Exo70; 1.
DR   SUPFAM; SSF74788; SSF74788; 1.
PE   3: Inferred from homology;
KW   Exocytosis; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..632
FT                   /note="Exocyst complex protein EXO70"
FT                   /id="PRO_0000118970"
SQ   SEQUENCE   632 AA;  69747 MW;  0782B65A0E8B37EE CRC64;
     MSVGLAGGAH TALDEEARAE VDVLNSRLEK TTQLTKKIQS CLNRLETTGK SVQDVAGPLN
     GETRRLQILG NNVDSVLAAI DRLRQPADSK NDEEQIIRVG PEKAGLSTYL ASIKRLGKAL
     AEMQASNLRA NQQTMADLSR LIKSGNSQLE HHFETVLRGE TPRSVEPLHY ITKDKPFPTL
     PQDKIARLGL IYSYVVESHH NGASELAHIY AEVRGPYLSA SLANLAAASV NTAKKKSPDA
     VYRAGTNGMG TYAQAMEGLF ISEYDNVCSV FSREDWGVIF LSTCQTALAE QARCLRELNA
     HIKSHLNTDC YLAYEITEII SALSGKLETR TGELKGALAA ALKPVRETAK SSLAELLEET
     RRKVGMLQIL PSDGAPIPLV SETMQRLQTM VHFLRPISSI MISIGDGGWK ANAATNGRST
     DAIPSLASFD IGADGKEIFS HYCLDTIEML LSGLDQKSRV LMKSRAVAGV FMANSVVIIG
     RMVQTSELND LLENKLDILE QWRKKATASY TDICKDLSVH LFDTVHTNRT NRPTSGPVDS
     TSIVKGLGSK DKDKIKEKFT QFNGAFDDMV SRHKSYSMER EVRRIFGEDI RQKLQPLYER
     FWDRYHEIDK GKGKYVKYDK TSIAAVFASL AS