ID   EXO70_YARLI             Reviewed;         603 AA.
AC   Q6CC70;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Exocyst complex protein EXO70;
GN   Name=EXO70; OrderedLocusNames=YALI0C11946g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in the secretory pathway as part of the exocyst
CC       complex which tethers secretory vesicles to the sites of exocytosis.
CC       Also plays a role in the assembly of the exocyst (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Bud {ECO:0000250}. Bud neck {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EXO70 family. {ECO:0000305}.
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DR   EMBL; CR382129; CAG82052.1; -; Genomic_DNA.
DR   RefSeq; XP_501742.1; XM_501742.1.
DR   AlphaFoldDB; Q6CC70; -.
DR   SMR; Q6CC70; -.
DR   STRING; 4952.CAG82052; -.
DR   PRIDE; Q6CC70; -.
DR   EnsemblFungi; CAG82052; CAG82052; YALI0_C11946g.
DR   GeneID; 2909275; -.
DR   KEGG; yli:YALI0C11946g; -.
DR   VEuPathDB; FungiDB:YALI0_C11946g; -.
DR   HOGENOM; CLU_010236_4_2_1; -.
DR   InParanoid; Q6CC70; -.
DR   OMA; GPIYGNT; -.
DR   Proteomes; UP000001300; Chromosome C.
DR   GO; GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.
DR   GO; GO:0000145; C:exocyst; IBA:GO_Central.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:InterPro.
DR   GO; GO:0006887; P:exocytosis; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR004140; Exo70.
DR   InterPro; IPR046364; Exo70_C.
DR   PANTHER; PTHR12542; PTHR12542; 1.
DR   Pfam; PF03081; Exo70; 1.
DR   SUPFAM; SSF74788; SSF74788; 1.
PE   3: Inferred from homology;
KW   Exocytosis; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..603
FT                   /note="Exocyst complex protein EXO70"
FT                   /id="PRO_0000118974"
SQ   SEQUENCE   603 AA;  67816 MW;  F564D497AB41E063 CRC64;
     MSLRPDEVDV RILEENLLKT NTLVESMVAS CQKISNSSYK AEITIEPISG MQRRMQVYET
     NLNNCLKVVD GIRDYAKVTA REEKIIRQGP EAVGLPAYVA AIQSVIRVND EIEQRKLHSI
     PKVKEKAVDL ARMGTSGLKE NLATILKEES NPIDPVPILA SGKPFPLMSP KNADKLNELM
     GIVARFSARQ DNTYVDSRSR YLAMSLSPVA SKVKPTVRTG KAPYDKQSNG IHIYAEALLK
     MLQAEHDNLR CAFPKDEARV KQYFTQLAQT PLQTYQAAGE EISNHVQRNI STDALLIFEL
     IEGTVALKRG LEPLTNSAAP LDRLIQSSYN VSQGVFTEIL KICEARVQQV MTLPSDNGVC
     DATVEVMSRI RRFAEYKDSA VLAISGMKYQ QWIPQPRPAW MSTFSSAPAG YTTTKPQELL
     SAVFSDSIDA FYVTLEMKAK QLNPKKPSQV GFFLLTNLTL IERFVTKSEV YKVLGGQGRE
     RLEKLRKRGL NLFLEGWKAT ASLLMDTTVV NSKGSLSSKD RELVKDKFKT FNADFEELVK
     NHKTYTITDP ALKQLLAKEV AFICPLYHRY YDKHIGGDFS KNVDKYIKYD KAQFDRVLQE
     LGD