ID   EXO84_GIBZE             Reviewed;         679 AA.
AC   Q4HYZ2; A0A0E0SEP1; V6RPQ4;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Exocyst complex component EXO84;
GN   Name=EXO84; ORFNames=FGRRES_09816, FGSG_09816;
OS   Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084
OS   / PH-1) (Wheat head blight fungus) (Fusarium graminearum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX   NCBI_TaxID=229533;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX   PubMed=17823352; DOI=10.1126/science.1143708;
RA   Cuomo C.A., Gueldener U., Xu J.-R., Trail F., Turgeon B.G., Di Pietro A.,
RA   Walton J.D., Ma L.-J., Baker S.E., Rep M., Adam G., Antoniw J., Baldwin T.,
RA   Calvo S.E., Chang Y.-L., DeCaprio D., Gale L.R., Gnerre S., Goswami R.S.,
RA   Hammond-Kosack K., Harris L.J., Hilburn K., Kennell J.C., Kroken S.,
RA   Magnuson J.K., Mannhaupt G., Mauceli E.W., Mewes H.-W., Mitterbauer R.,
RA   Muehlbauer G., Muensterkoetter M., Nelson D., O'Donnell K., Ouellet T.,
RA   Qi W., Quesneville H., Roncero M.I.G., Seong K.-Y., Tetko I.V., Urban M.,
RA   Waalwijk C., Ward T.J., Yao J., Birren B.W., Kistler H.C.;
RT   "The Fusarium graminearum genome reveals a link between localized
RT   polymorphism and pathogen specialization.";
RL   Science 317:1400-1402(2007).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX   PubMed=20237561; DOI=10.1038/nature08850;
RA   Ma L.-J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.-J.,
RA   Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA   Houterman P.M., Kang S., Shim W.-B., Woloshuk C., Xie X., Xu J.-R.,
RA   Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA   Butchko R.A.E., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.J.,
RA   Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA   Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA   Kumar L., Lee Y.-H., Li L., Manners J.M., Miranda-Saavedra D.,
RA   Mukherjee M., Park G., Park J., Park S.-Y., Proctor R.H., Regev A.,
RA   Ruiz-Roldan M.C., Sain D., Sakthikumar S., Sykes S., Schwartz D.C.,
RA   Turgeon B.G., Wapinski I., Yoder O., Young S., Zeng Q., Zhou S.,
RA   Galagan J., Cuomo C.A., Kistler H.C., Rep M.;
RT   "Comparative genomics reveals mobile pathogenicity chromosomes in
RT   Fusarium.";
RL   Nature 464:367-373(2010).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX   PubMed=26198851; DOI=10.1186/s12864-015-1756-1;
RA   King R., Urban M., Hammond-Kosack M.C.U., Hassani-Pak K.,
RA   Hammond-Kosack K.E.;
RT   "The completed genome sequence of the pathogenic ascomycete fungus Fusarium
RT   graminearum.";
RL   BMC Genomics 16:544-544(2015).
CC   -!- FUNCTION: Involved in the secretory pathway as part of the exocyst
CC       complex which tethers secretory vesicles to the sites of exocytosis.
CC       Plays a role in both the assembly of the exocyst and the polarization
CC       of this complex to specific sites of the plasma membrane for
CC       exocytosis. Also involved in assembly of the spliceosome (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the exocyst complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle
CC       {ECO:0000250}. Note=Cell periphery. The polarization of EXO84 requires
CC       actin cables (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EXO84 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS231668; ESU16446.1; -; Genomic_DNA.
DR   EMBL; HG970335; CEF84904.1; -; Genomic_DNA.
DR   RefSeq; XP_011327870.1; XM_011329568.1.
DR   AlphaFoldDB; Q4HYZ2; -.
DR   SMR; Q4HYZ2; -.
DR   STRING; 5518.FGSG_09816P0; -.
DR   PRIDE; Q4HYZ2; -.
DR   EnsemblFungi; ESU16446; ESU16446; FGSG_09816.
DR   GeneID; 23556748; -.
DR   KEGG; fgr:FGSG_09816; -.
DR   VEuPathDB; FungiDB:FGRAMPH1_01G26209; -.
DR   eggNOG; KOG2215; Eukaryota.
DR   HOGENOM; CLU_012488_2_0_1; -.
DR   InParanoid; Q4HYZ2; -.
DR   Proteomes; UP000070720; Chromosome 4.
DR   GO; GO:0000145; C:exocyst; IEA:InterPro.
DR   GO; GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.58.1210; -; 1.
DR   Gene3D; 1.20.58.1220; -; 1.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR033961; Exo84.
DR   InterPro; IPR032403; Exo84_C.
DR   InterPro; IPR042561; Exo84_C_1.
DR   InterPro; IPR042560; Exo84_C_2.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   PANTHER; PTHR21426; PTHR21426; 2.
DR   Pfam; PF16528; Exo84_C; 1.
DR   SUPFAM; SSF74788; SSF74788; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasmic vesicle; Exocytosis; Protein transport;
KW   Reference proteome; Transport.
FT   CHAIN           1..679
FT                   /note="Exocyst complex component EXO84"
FT                   /id="PRO_0000118982"
FT   REGION          1..123
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          214..237
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          142..208
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        71..88
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   679 AA;  76462 MW;  DFDEFEE1AFE6CD77 CRC64;
     MEDRNKISLR SGRRKKRPTI SAPRQISGPI AQDDSNRPPL PGADPSQASA QPRPRPPPMA
     GGKTSDLVKR RYSTRFNQPS SISNGGAPPM PQMPSLANYE PRETVAAARK PPSRSGPGVA
     PVIDIKGLRD PKLKPDRYVQ AALSDATEDQ IREFEESLRQ VKTRVGTDLQ QSVMQNRTQF
     IKISKEAEKL KSEMRNLKNF MSELKVNTTA MRAAAAKSDE PMPSDLGVAP GISSRRDRRT
     SIADRSAMWN SQMQALYKGV EGSQKFLPNA VGRHVVQDAG PWIELDNATY KSRRAMQIFL
     LNDHLLIASR KKRKADAPGA DARGPMMKLV ADRCWPLLDV EVVDMSSTGE SSNSGRNKLA
     DAIMVRGVGQ ESFIYRTEKP QDPEKKQLLL NVRKAIEQLR KGLRSEMEAN NKARETINYF
     ASRDPGLLQK TELLATLSDI KDMLIEVDGK QQNLRWVESE MDDLDIDVAM QRFEDAVVRV
     EKLKAIARGL KNHAIAQDFI NFKVNERCVR LANMIGRELE MTHDNNTKTR RNVSWLTRLG
     FEDSARESYL AARSGTIHKR TRQCIFQGDL HLYIWELSFV YFMVIHNTVQ CFQSCFPPPM
     MSVCVKWAKE EVDAFNIILA RQLSSTELRG QVWTQCMERA KEHSKLLSEV GLDFENLVGK
     NLMIYEPIDQ GPSVGLGLS