ID   EXO84_YARLI             Reviewed;         657 AA.
AC   Q6C238;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Exocyst complex component EXO84;
GN   Name=EXO84; OrderedLocusNames=YALI0F11143g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in the secretory pathway as part of the exocyst
CC       complex which tethers secretory vesicles to the sites of exocytosis.
CC       Plays a role in both the assembly of the exocyst and the polarization
CC       of this complex to specific sites of the plasma membrane for
CC       exocytosis. Also involved in assembly of the spliceosome (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the exocyst complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle
CC       {ECO:0000250}. Note=Cell periphery. The polarization of EXO84 requires
CC       actin cables (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EXO84 family. {ECO:0000305}.
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DR   EMBL; CR382132; CAG78081.1; -; Genomic_DNA.
DR   RefSeq; XP_505274.1; XM_505274.1.
DR   AlphaFoldDB; Q6C238; -.
DR   SMR; Q6C238; -.
DR   STRING; 4952.CAG78081; -.
DR   PRIDE; Q6C238; -.
DR   EnsemblFungi; CAG78081; CAG78081; YALI0_F11143g.
DR   GeneID; 2908180; -.
DR   KEGG; yli:YALI0F11143g; -.
DR   VEuPathDB; FungiDB:YALI0_F11143g; -.
DR   HOGENOM; CLU_012488_2_0_1; -.
DR   InParanoid; Q6C238; -.
DR   OMA; SACVKWA; -.
DR   Proteomes; UP000001300; Chromosome F.
DR   GO; GO:0000145; C:exocyst; IBA:GO_Central.
DR   GO; GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006893; P:Golgi to plasma membrane transport; IBA:GO_Central.
DR   GO; GO:0008104; P:protein localization; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.58.1210; -; 1.
DR   Gene3D; 1.20.58.1220; -; 1.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR033961; Exo84.
DR   InterPro; IPR032403; Exo84_C.
DR   InterPro; IPR042561; Exo84_C_1.
DR   InterPro; IPR042560; Exo84_C_2.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   PANTHER; PTHR21426; PTHR21426; 2.
DR   Pfam; PF16528; Exo84_C; 1.
DR   SUPFAM; SSF74788; SSF74788; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasmic vesicle; Exocytosis; Protein transport;
KW   Reference proteome; Transport.
FT   CHAIN           1..657
FT                   /note="Exocyst complex component EXO84"
FT                   /id="PRO_0000118986"
FT   COILED          142..165
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   657 AA;  72574 MW;  3BB066B85D880AD0 CRC64;
     MSLEPPNQSL RSHRQTANPH VMAAAVQKQK PYIQDSTHLQ LPNVGDKDRE RVGNMVKRRF
     SARIPGQGVP YDAAAAPSLP VGAGSMIDDA VAAGGVPVTK SKTMTSPAKA APVASGASGM
     LLKEDLDAHT FVTQQLATSN AEEVDRFVSK LKSLKSRLVD EQREAMYTNY NSFLTVNKEI
     LALNSEVKSL GQAVSNFNVA VSAMVEDALE STSSKSQESS QSSLALPDSS ARNRNSMVML
     ENMWANELAS LFKHVEGAVK YLPAIPGRHV VAESGAWYQL NAATWKPLRP VHMFLLNDHL
     LIAAKNRKKD NMQMQQTQTL VADQCWPLSD IEFLDLSVSR RGTHPVVPNA VSVVCGGVTC
     VYQTEKPAQH AKVVSAFKKV AGEGRKNDTN KTQQQIRLRE SMTYYAARNP SLRGHKELLQ
     GLSNSKGHSR SSSVDITGRT KNLREIDDLV NDLDVKIAHR RFAEATDIIL ENIKDDKEST
     DITQQVLDIK LHQRQDELVA HLIDDVATDT SNTAVTHALG LLVRLGHGDQ ARGVYLETRR
     NLIHKRTRQV ELLGDIPGYI AQVAVTYFRL IRSTAEVFRK CYTDNHLASS IAEWAKSMVE
     EFVLLFARQL YGVKPDTQTY QQCVSITRQQ AAQLSEVGLN LDYLLDYVLS PARASKA