ID   EXOC3_CAEEL             Reviewed;         796 AA.
AC   Q19262;
DT   25-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 2.
DT   03-AUG-2022, entry version 131.
DE   RecName: Full=Exocyst complex component 3;
DE   AltName: Full=Exocyst complex component Sec6;
GN   Name=sec-6; ORFNames=F09E5.5;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Component of the exocyst complex involved in the docking of
CC       exocytic vesicles with fusion sites on the plasma membrane.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: The exocyst complex is composed of sec-3/exoc1, sec-5/exoc2,
CC       sec-6/exoc3, sec-8/exoc4, sec-10/exoc5, sec-15/exoc6, exo-70/exoc7 and
CC       exo-84/exoc8. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SEC6 family. {ECO:0000305}.
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DR   EMBL; FO081044; CCD68758.1; -; Genomic_DNA.
DR   PIR; T16002; T16002.
DR   RefSeq; NP_495006.2; NM_062605.7.
DR   AlphaFoldDB; Q19262; -.
DR   SMR; Q19262; -.
DR   BioGRID; 39255; 11.
DR   ComplexPortal; CPX-712; Exocyst.
DR   STRING; 6239.F09E5.5.2; -.
DR   EPD; Q19262; -.
DR   PaxDb; Q19262; -.
DR   PeptideAtlas; Q19262; -.
DR   EnsemblMetazoa; F09E5.5.1; F09E5.5.1; WBGene00017284.
DR   EnsemblMetazoa; F09E5.5.2; F09E5.5.2; WBGene00017284.
DR   GeneID; 173910; -.
DR   KEGG; cel:CELE_F09E5.5; -.
DR   UCSC; F09E5.5.2; c. elegans.
DR   CTD; 173910; -.
DR   WormBase; F09E5.5; CE29752; WBGene00017284; sec-6.
DR   eggNOG; KOG2286; Eukaryota.
DR   GeneTree; ENSGT01030000234613; -.
DR   HOGENOM; CLU_016260_1_0_1; -.
DR   InParanoid; Q19262; -.
DR   OMA; MNIGPKT; -.
DR   OrthoDB; 391172at2759; -.
DR   PhylomeDB; Q19262; -.
DR   Reactome; R-CEL-264876; Insulin processing.
DR   Reactome; R-CEL-5620916; VxPx cargo-targeting to cilium.
DR   PRO; PR:Q19262; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00017284; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR   GO; GO:0000145; C:exocyst; ISS:WormBase.
DR   GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR   GO; GO:0051601; P:exocyst localization; IBA:GO_Central.
DR   GO; GO:0006887; P:exocytosis; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0090522; P:vesicle tethering involved in exocytosis; IMP:ComplexPortal.
DR   Gene3D; 1.10.357.70; -; 1.
DR   InterPro; IPR010326; EXOC3/Sec6.
DR   InterPro; IPR042532; EXOC3/Sec6_C.
DR   PANTHER; PTHR21292; PTHR21292; 1.
DR   Pfam; PF06046; Sec6; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Exocytosis; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..796
FT                   /note="Exocyst complex component 3"
FT                   /id="PRO_0000118928"
FT   COILED          87..174
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   796 AA;  90654 MW;  C1F0DA3CF24FD284 CRC64;
     MDVDVEEAAL EQVAALLQRP DQLEKLPELK KRADRKKLAV EAMLRTGVQG QLEGIRTAIA
     HLQTASDDIT AISQGVHDIR ERLGPFPQLK EKLRELRDAN ARHGQYAAAM ENLKHIFNLQ
     TTLQEIRDAL DDEKSGGNLL LAHKHIMDLE RARDELLAEV HKMSGTNTEK EQMLLVNFFK
     GVDSVVAELS KNMWFILGRT LEMVKGNEQG GGPQQVVTCL RIVEREERID KFYMEARSKN
     SSAFVPPGRP RNWKEKALRS LEKTVSNRVD GNQLEDRSLN KAWLARYLEV CKNVIMDDLQ
     LAKVAIPCFP PDWQIYDRYV HMYHTSVCRR LREVASEHLE KSELVQLMSW IKFYASEDML
     GHPKLRINAQ AILQDSPVLS RSTLNQLCDQ FVEMSRDDLK LWLKNTVSHE THDWYKNLRP
     SEDNHGYFYT DLPNTVFGML KDTVTLAKEV SVEVIPSIIN LTIQEFNELA GKYRDAFTAY
     KTDYFAERSK YQEFTSNIIA IANNLHTCIE STEKYKQQIR LSMEGEQNAA AAMTTPLASG
     RRTAVRQQQL IENMDALNTK WSNAASVAVN YLREEVITDI APSLVEIFSK KWLTGSAALE
     TVCMTISDYY HDHKHLRPVT RSTLLMDLQF RIVSEYLKAI ETKRVSLNSY EERALAGKRM
     KADVVRLDNL YAEFATSSDM ADQLPLLTSI VAAAGDVISL KDKSLLSLEA TSFARKFPNC
     PAELLSAVIA TRDDISGSEA RSLASEVLQH VQFHPKDQIF DQLFALRQQE NSERLPNLGM
     ANMFKADFMS MLKRDA