ID   EXOC5_DICDI             Reviewed;         978 AA.
AC   B0G163;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Exocyst complex component 5;
DE   AltName: Full=Exocyst complex component Sec10;
GN   Name=exoc5; Synonyms=sec10; ORFNames=DDB_G0287881;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Component of the exocyst complex involved in the docking of
CC       exocytic vesicles with fusion sites on the plasma membrane.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: The exocyst complex is composed of sec3/exoc1, sec5/exoc2,
CC       sec6/exoc3, sec8/exoc4, sec10/exoc5, sec15/exoc6, exo70/exoc7 and
CC       exo84/exoc8. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SEC10 family. {ECO:0000305}.
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DR   EMBL; AAFI02000104; EDR41045.1; -; Genomic_DNA.
DR   RefSeq; XP_001733026.1; XM_001732974.1.
DR   AlphaFoldDB; B0G163; -.
DR   SMR; B0G163; -.
DR   STRING; 44689.DDB0233963; -.
DR   PaxDb; B0G163; -.
DR   PRIDE; B0G163; -.
DR   EnsemblProtists; EDR41045; EDR41045; DDB_G0287881.
DR   GeneID; 8626283; -.
DR   KEGG; ddi:DDB_G0287881; -.
DR   dictyBase; DDB_G0287881; exoc5.
DR   eggNOG; KOG3745; Eukaryota.
DR   HOGENOM; CLU_304107_0_0_1; -.
DR   InParanoid; B0G163; -.
DR   OMA; PLCKHHY; -.
DR   PhylomeDB; B0G163; -.
DR   Reactome; R-DDI-264876; Insulin processing.
DR   PRO; PR:B0G163; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0000145; C:exocyst; IDA:dictyBase.
DR   GO; GO:0006887; P:exocytosis; IBA:GO_Central.
DR   GO; GO:0006893; P:Golgi to plasma membrane transport; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR033960; EXOC5/Sec10.
DR   InterPro; IPR009976; Sec10-like.
DR   PANTHER; PTHR12100; PTHR12100; 1.
DR   PANTHER; PTHR12100:SF0; PTHR12100:SF0; 1.
DR   Pfam; PF07393; Sec10; 2.
PE   3: Inferred from homology;
KW   Coiled coil; Exocytosis; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..978
FT                   /note="Exocyst complex component 5"
FT                   /id="PRO_0000329038"
FT   REGION          1..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          122..246
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          303..325
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   978 AA;  110105 MW;  94118AF23EE3A64E CRC64;
     MSWARNIQSR IQQQQQLQKP GGLAPPSGNE TPQKQPSSPT LSALSSPITS LTNALRGSGG
     ISQPTTNTTS LTSTSPPSPT ISTTTTQVKV GQTSFTTSTN LQAAASGNNL QASIQTTNIT
     VTSPSMASPI GTSTGIQNPN AKPSSLPSPS QSPMQTRNTS APTNNNNNNN TATTTTPTTT
     TTTTTTTTTT TTTTTTPSTS TTTTPTTSSS NLGQIQQQPP TLQQQQQQIQ QQQQQQPTPI
     KQTTPYIFPN KIQPKSLTTD MFRGSEFSHV TFVEDLTRKL VNDQMGADGL HFEPAPFNQL
     FLNTQLQLSQ LESNIDRRLD DLAEECNDFS YDYKRKLQDL TGSYQECFQH FKKLEKGVNT
     IGTKAVHFGD ELDSVNQQKV KAQGALSLIN YLLELNSVGA SSEENGGITK RSDIFTNSDR
     IHELAHLVKK LSSVSEDIKE ISGFKQGKLE TESISNSLEN DLLNQFERAA ERNDYDKMKQ
     CATTLHGFNG GERCRSRYIQ KLKMFFDIDS FRKDENLANN ITKRLIRGNN IVDTRFEIFY
     TDILKDVSHE QMVIQNVFVN QTSAMAMLII RLFEQRVRLF IENVLSLESN NVSMFLQTVH
     YAFNSTKKLL VDPLQSYGIV GVDLNQLLNS IFYQYQEGYI QKETTYLVSL FQSNVVEECE
     RLQTLDRYSM YLEDGLNPEI TQMFVQQTEN ALTRSYTLSL DNILADNIKT IFFLMLEYLF
     EKYSMFVLNK YIELPMIPSS SSNVDTKSIQ DSISQLFRVV LSINQIVGQI QSMFQVFVLP
     HIQTSMIVQS QCSDQLYFNI SSLENTINTG LENSLTTMIQ LIEKTLLPQG RNDYLIDDYD
     NSVTDTCASV IKLIQSFYDM AKINLQGKNF HIYVEELGLK SQFVFINHFK KFKIGQGIGT
     LKLMRDLTEY RNLSKQFKSQ KVDDAFELLF EISKLHLVNP ENFKLVIEGG ALTRMSKQDL
     IIFIKQRSDF KSIWLDTL