ID   EXOM_RHIME              Reviewed;         309 AA.
AC   P33695;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Succinoglycan biosynthesis protein ExoM;
DE            EC=2.4.-.-;
GN   Name=exoM; OrderedLocusNames=RB1083; ORFNames=SMb20958;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OG   Plasmid pSymB (megaplasmid 2).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=8226645; DOI=10.1128/jb.175.21.7033-7044.1993;
RA   Glucksmann M.A., Reuber T.L., Walker G.C.;
RT   "Family of glycosyl transferases needed for the synthesis of succinoglycan
RT   by Rhizobium meliloti.";
RL   J. Bacteriol. 175:7033-7044(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=RCR2011 / SU47;
RX   PubMed=8246891; DOI=10.1007/bf00284690;
RA   Becker A., Kleickmann A., Keller M., Arnold W., Puehler A.;
RT   "Identification and analysis of the Rhizobium meliloti exoAMONP genes
RT   involved in exopolysaccharide biosynthesis and mapping of promoters located
RT   on the exoHKLAMONP fragment.";
RL   Mol. Gen. Genet. 241:367-379(1993).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481431; DOI=10.1073/pnas.161294698;
RA   Finan T.M., Weidner S., Wong K., Buhrmester J., Chain P., Vorhoelter F.J.,
RA   Hernandez-Lucas I., Becker A., Cowie A., Gouzy J., Golding B., Puehler A.;
RT   "The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing
RT   endosymbiont Sinorhizobium meliloti.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9889-9894(2001).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   -!- FUNCTION: Glycosyltransferase required for the synthesis of
CC       succinoglycan (EPS I). Needed for the addition of the fourth sugar
CC       (glucose), catalyzes the formation of a beta-1,4 linkage between the
CC       third acetylated sugar and the fourth sugar.
CC   -!- PATHWAY: Glycan metabolism; exopolysaccharide biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. {ECO:0000305}.
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DR   EMBL; L20758; AAA16045.1; -; Unassigned_DNA.
DR   EMBL; Z22636; CAA80346.1; -; Genomic_DNA.
DR   EMBL; AL591985; CAC49483.1; -; Genomic_DNA.
DR   PIR; C95977; C95977.
DR   PIR; S37028; S37028.
DR   PIR; S39957; S39957.
DR   RefSeq; NP_437623.1; NC_003078.1.
DR   RefSeq; WP_010975919.1; NC_003078.1.
DR   AlphaFoldDB; P33695; -.
DR   SMR; P33695; -.
DR   STRING; 266834.SM_b20958; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   EnsemblBacteria; CAC49483; CAC49483; SM_b20958.
DR   GeneID; 61601038; -.
DR   KEGG; sme:SM_b20958; -.
DR   PATRIC; fig|266834.11.peg.6011; -.
DR   eggNOG; COG1215; Bacteria.
DR   HOGENOM; CLU_025996_3_0_5; -.
DR   OMA; FDYPLIR; -.
DR   BioCyc; MetaCyc:SM_B20958-MON; -.
DR   UniPathway; UPA00631; -.
DR   Proteomes; UP000001976; Plasmid pSymB.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Exopolysaccharide synthesis;
KW   Glycosyltransferase; Membrane; Plasmid; Reference proteome; Transferase.
FT   CHAIN           1..309
FT                   /note="Succinoglycan biosynthesis protein ExoM"
FT                   /id="PRO_0000059182"
FT   CONFLICT        169
FT                   /note="A -> R (in Ref. 2; CAA80346)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   309 AA;  33705 MW;  A85CA66C7F57667E CRC64;
     MPNETLHIDI GVCTYRRPEL AETLRSLAAM NVPERARLRV IVADNDAEPS ARALVEGLRP
     EMPFDILYVH CPHSNISIAR NCCLDNSTGD FLAFLDDDET VSGDWLTRLL ETARTTGAAA
     VLGPVRAHYG PTAPRWMRSG DFHSTLPVWA KGEIRTGYTC NALLRRDAAS LLGRRFKLSL
     GKSGGEDTDF FTGMHCAGGT IAFSPEAWVH EPVPENRASL AWLAKRRFRS GQTHGRLLAE
     KAHGLRQAWN IALAGAKSGF CATAAVLCFP SAARRNRFAL RAVLHAGVIS GLLGLKEIEQ
     YGAREVTSA